Evidence map›Paper›PMID 38317714›Full record

ReviewFrontiers in endocrinology2023

Divergent roles of the regulatory subunits of class IA PI3K.

Cho-Won Kim, Junsik M Lee, Sang Won Park

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Insulin Resistance and Inflammation.International journal of molecular sciences · 2026
    Review
  4. PI3 K/AKT/mTOR pathway and its role in breast cancer stem cells.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cho-Won KimDivision of Endocrinology, Boston Children's Hospital, Boston, MA, United States.
Junsik M LeeDivision of Endocrinology, Boston Children's Hospital, Boston, MA, United States.
Sang Won ParkDivision of Endocrinology, Boston Children's Hospital, Boston, MA, United States.

Funding

The regulation of BRD7 in glucose homeostasisR01DK118244 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI PARK, SANG WON · 2019 to 2023
$2.2M
NIDDK NIH HHS R01 DK118244
6 · The paper itself

Abstract

The regulatory subunit of phosphatidylinositol 3-kinase (PI3K), known as p85, is a critical component in the insulin signaling pathway. Extensive research has shed light on the diverse roles played by the two isoforms of p85, namely p85α and p85β. The gene

Indexed as

HyperinsulinismInsulin ResistanceNeoplasmsAnimalsClass Ia Phosphatidylinositol 3-KinaseGlucoseInsulinMiceMice, KnockoutPhosphatidylinositol 3-KinasesProtein IsoformsClass Ia Phosphatidylinositol 3-KinaseGlucoseInsulinPhosphatidylinositol 3-KinasesProtein Isoformscancerglucose metabolisminsulin signalingp85PI3K

Identifiers

PMID38317714
PMCPMC10839044

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.