Evidence map›Paper›PMID 38317557›Full record

ArticleNeurospine2024

Severe Preoperative Disability Is Associated With Greater Mental Health Improvements Following Surgery for Degenerative Spondylolisthesis: A Cohort Matched Analysis.

Ishan Khosla, Fatima N Anwar, Andrea M Roca, Srinath S Medakkar, Alexandra C Loya, Aayush Kaul, Jacob C Wolf, Vincent P Federico, Arash J Sayari, Gregory D Lopez and 1 more

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Article in Neurospine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ishan KhoslaDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Fatima N AnwarDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Andrea M RocaDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Srinath S MedakkarDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Alexandra C LoyaDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Aayush KaulChicago Medical School at Rosalind Franklin University of Medicine and Science, Chicago, IL, USA.
Jacob C WolfChicago Medical School at Rosalind Franklin University of Medicine and Science, Chicago, IL, USA.
Vincent P FedericoDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Arash J SayariDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Gregory D LopezDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Kern SinghDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate preoperative disability's influence on patient-reported outcomes (PROs) following surgery for degenerative spondylolisthesis (DS).

methodsDS patients who underwent surgical intervention were retrospectively identified from a single-surgeon spine registry. Cohorts based on Oswestry Disability Index (ODI) < 41 (milder disability) and ≥ 41 (severe disability) were created. Demographic differences were accounted for with 1:1 propensity score matching. For the matched sample, perioperative and PRO data were additionally collected. PROs assessed included mental health, physical function, pain, and disability. Pre- and up to 2-year postoperative PROs were utilized. Average time to final follow-up was 15.7 ± 8.8 months. Improvements in PROs and minimal clinically important difference (MCID) rates were calculated. Continuous variables were compared through Student t-test and categorical variables were compared through chi-square tests.

resultsAltogether, 214 patients were included with 77 in the milder disability group. The severe disability group had worse postoperative day (POD) 1 pain scores and longer hospital stays (p ≤ 0.038, both). The severe disability group reported worse outcomes pre- and postoperatively (p < 0.011, all), but had greater average improvement in 12-item Short Form health survey mental composite score (SF-12 MCS), 9-Item Patient Health Questionnaire (PHQ-9), visual analogue scale (VAS)-back, and ODI by 6 weeks (p ≤ 0.037, all) and PHQ-9, VAS-back and ODI by final follow-up (p ≤ 0.015, all). The severe disability cohort was more likely to achieve MCID for SF-12 MCS, PHQ-9, and ODI (p ≤ 0.003, all).

conclusionPatients with greater baseline disability report higher POD 1 pain and discharge later than patients with milder disability. While these patients report inferior physical/mental health before and after surgery, they report greater improvements in mental health and disability postoperatively.

Indexed as

Degenerative spondylolisthesisDisabilityMental healthPatient-reported outcomes

Identifiers

PMID38317557
PMCPMC10992647

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