Evidence map›Paper›PMID 38317201›Full record

ArticleEuropean journal of medical research2024

Effects of training flights of combat jet pilots on parameters of airway function, diffusing capacity and systemic oxidative stress, and their association with flight parameters.

Janina Bojahr, Rudolf A Jörres, Angelika Kronseder, Frank Weber, Carla Ledderhos, Immanuel Roiu, Stefan Karrasch, Dennis Nowak, Daniel Teupser, Christian Königer

Abstract read
In one paragraph

Article in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Janina BojahrInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), University Hospital, LMU Munich, Munich, Germany. janina.bojahr@gmail.com.
Rudolf A JörresInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), University Hospital, LMU Munich, Munich, Germany.
Angelika KronsederInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), University Hospital, LMU Munich, Munich, Germany.
Frank WeberAir Force Centre of Aerospace Medicine, Fuerstenfeldbruck, Cologne, Germany.
Carla LedderhosAir Force Centre of Aerospace Medicine, Fuerstenfeldbruck, Cologne, Germany.
Immanuel Roiu74th Tactical Air Wing of the German Air Force, Neuburg, Germany.
Stefan KarraschInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), University Hospital, LMU Munich, Munich, Germany.
Dennis NowakInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), University Hospital, LMU Munich, Munich, Germany.
Daniel TeupserInstitute for Laboratory Medicine, University Hospital, LMU Munich, Munich, Germany.
Christian KönigerAir Force Centre of Aerospace Medicine, Fuerstenfeldbruck, Cologne, Germany.

Funding

German Air Force Centre of Aerospace Medicine no specific grant
6 · The paper itself

Abstract

backgroundFighter aircraft pilots are regularly exposed to physiological challenges from high acceleration (G

methodsThirty-five pilots of the German Air Force performed 145 flights with the Eurofighter Typhoon. Prior to and after flight lung diffusing capacity for carbon monoxide (DL

resultsDL

conclusionsThe pattern of reductions in diffusing capacities suggests effects arising from atelectasis and increased diffusion barrier, without changes in capillary blood volume. The decrease in exhaled endogenous NO suggests bronchial mucosal irritation and/or local oxidative stress, and the increase in urinary oxidized guanosine species suggests systemic oxidative stress. Although changes were small and not clinically relevant, their presence demonstrated physiological effects of real training flights in a modern 4th generation fighter jet.

Indexed as

LungNitric OxideHumansPulmonary Diffusing CapacityNitric OxideDiffusing capacityExhaled nitric oxideG-forcesJet fighter pilotsLife support systemLung functionOxidized guanosine speciesPositive pressure breathing

Identifiers

PMID38317201
PMCPMC10840181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.