Evidence map›Paper›PMID 38316553›Full record

ReviewCold Spring Harbor perspectives in biology2024

Astrocyte Regulation of Cerebral Blood Flow in Health and Disease.

Anusha Mishra, Grant R Gordon, Brian A MacVicar, Eric A Newman

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  3. Prolonged systemic inflammation worsens impairments to astrocyte CaAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Article
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  7. Review
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  12. Prolonged systemic inflammation worsens impairments to astrocyte CabioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IPProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Anusha Mishra *Department of Neurology, Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, Oregon 97239, USA.
Grant R Gordon *Hotchkiss Brain Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
Brian A MacVicarDjavad Mowafaghian Centre for Brain Health, Department of Psychiatry, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Eric A NewmanDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455, USA ean@umn.edu.
Center for Neurosciences · USUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Minnesota · US

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
PHYSIOLOGY OF RETINAL MULLER CELLS AND ASTROCYTESR01EY004077 · NEI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI NEWMAN, ERIC A · 1985 to 2013
$5.7M
Astrocyte regulation of cerebral blood flow during hypoglycemiaR01NS126166 · NINDS · UNIVERSITY OF MINNESOTA · PI ERIC A NEWMAN · 2022 to 2026
$1.9M
Regulation of Capillary Blood Flow in the Retina in Health and in Diabetic RetinopathyR01EY026514 · NEI · UNIVERSITY OF MINNESOTA · PI NEWMAN, ERIC A · 2016 to 2020
$1.9M
Glial cell regulation of blood flow in capillariesR01EY026882 · NEI · UNIVERSITY OF MINNESOTA · PI NEWMAN, ERIC A · 2016 to 2020
$1.7M
Glial regulation of neurovascular coupling in CNS disordersR01NS110690 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MISHRA, ANUSHA · 2019 to 2023
$1.7M
Dark adaptation and hypoxia in diabetic retinopathyR21EY023216 · NEI · UNIVERSITY OF MINNESOTA · PI NEWMAN, ERIC A · 2013 to 2014
$414k
NEI NIH HHS R01 EY004077NEI NIH HHS R01 EY026514NEI NIH HHS R01 EY026882NEI NIH HHS R21 EY023216NIA NIH HHS P30 AG066518NINDS NIH HHS R01 NS110690NINDS NIH HHS R01 NS126166
6 · The paper itself

Abstract

Astrocytes play an important role in controlling microvascular diameter and regulating local cerebral blood flow (CBF) in several physiological and pathological scenarios. Neurotransmitters released from active neurons evoke Ca

Indexed as

AstrocytesCerebrovascular CirculationNeuronsProstaglandinsProstaglandins

Identifiers

PMID38316553
PMCPMC10982716
OpenAlexW4391528119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.