Evidence map›Paper›PMID 38316143›Full record

ReviewAnnual review of clinical psychology2024

Intervention Optimization: A Paradigm Shift and Its Potential Implications for Clinical Psychology.

Linda M Collins, Inbal Nahum-Shani, Kate Guastaferro, Jillian C Strayhorn, David J Vanness, Susan A Murphy

Registry-linked trialAbstract readReview
In one paragraph

Review in Annual review of clinical psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07609342 (Optimizing a School-Based Therapeutic Play Intervention for Preschool Students), which is not on this map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07609342 narecruitingnot on this map

Optimizing a School-Based Therapeutic Play Intervention for Preschool Students: A Factorial Experiment Protocol

TypeinterventionalSponsorThe Children's InstituteRan2024 to 2027Enrolled225ConditionsSocioemotional DevelopmentArmsIndividual play sessions, Peer play sessions, Classroom push-in sessions
3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

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  6. Article
  7. Identifying the active ingredients of a behavioral activation-based digital single-session intervention targeting depression.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  8. Article
  9. Power Calculation in 2Prevention science : the official journal of the Society for Prevention Research · 2026
    Article
  10. Review
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linda M CollinsDepartment of Social and Behavioral Sciences, New York University, New York, NY, USA; email: lmc9580@nyu.edu.
Inbal Nahum-ShaniInstitute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.
Kate GuastaferroDepartment of Social and Behavioral Sciences, New York University, New York, NY, USA; email: lmc9580@nyu.edu.
Jillian C StrayhornDepartment of Social and Behavioral Sciences, New York University, New York, NY, USA; email: lmc9580@nyu.edu.
David J VannessDepartment of Health Policy and Administration, The Pennsylvania State University, University Park, Pennsylvania, USA.
Susan A MurphyDepartments of Statistics and Computer Science, Harvard University, Cambridge, Massachusetts, USA.

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
Pilot and Mentoring CoreP50DA054039 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LINDA M COLLINS, SUSAN A MURPHY · 2021 to 2026
$18.2M
Pilot, Mentoring, and Professional Development CoreP50DA039838 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI COLLINS, LINDA M · 2015 to 2019
$13.9M
Novel Methods for Intensive Longitudinal Data in SMART Studies of Drug Abuse and HIVR01DA039901 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALMIRALL, DANIEL, NAHUM-SHANI, INBAL BILLIE · 2015 to 2024
$5.4M
NIDA NIH HHS P30 DA011041NIDA NIH HHS P50 DA039838NIDA NIH HHS P50 DA054039NIDA NIH HHS R01 DA039901
6 · The paper itself

Abstract

To build a coherent knowledge base about what psychological intervention strategies work, develop interventions that have positive societal impact, and maintain and increase this impact over time, it is necessary to replace the classical treatment package research paradigm. The multiphase optimization strategy (MOST) is an alternative paradigm that integrates ideas from behavioral science, engineering, implementation science, economics, and decision science. MOST enables optimization of interventions to strategically balance effectiveness, affordability, scalability, and efficiency. In this review we provide an overview of MOST, discuss several experimental designs that can be used in intervention optimization, consider how the investigator can use experimental results to select components for inclusion in the optimized intervention, discuss the application of MOST in implementation science, and list future issues in this rapidly evolving field. We highlight the feasibility of adopting this new research paradigm as well as its potential to hasten the progress of psychological intervention science.

Indexed as

Psychology, ClinicalHumansImplementation SciencePsychosocial InterventionPsychotherapyResearch Designadaptive interventionfactorial experimentintervention optimizationmicro-randomized trialmultiphase optimization strategysequential multiple assignment randomized trial

Identifiers

PMID38316143
PMCPMC11245367

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.