Evidence map›Paper›PMID 38316139›Full record

ArticleACS synthetic biology2024

The SARS-CoV-2 M

Ernawati Arifin Giri-Rachman, Vergio V Effendy, Muhammad H S Azmi, Nicholas Yamahoki, Rebecca Stephanie, Dian F Agustiyanti, Popi H Wisnuwardhani, Marissa Angelina, Yana Rubiyana, Reza Aditama and 3 more

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Ernawati Arifin Giri-RachmanSchool of Life Sciences and Technology, Institut Teknologi Bandung, Bandung 40132, Indonesia.ORCID 0009-0009-2325-5763
Vergio V EffendySchool of Life Sciences and Technology, Institut Teknologi Bandung, Bandung 40132, Indonesia.
Muhammad H S AzmiSchool of Life Sciences and Technology, Institut Teknologi Bandung, Bandung 40132, Indonesia.
Nicholas YamahokiSchool of Life Sciences and Technology, Institut Teknologi Bandung, Bandung 40132, Indonesia.
Rebecca StephanieSchool of Life Sciences and Technology, Institut Teknologi Bandung, Bandung 40132, Indonesia.
Dian F AgustiyantiResearch Center for Genetic Engineering, Indonesian National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia.
Popi H WisnuwardhaniResearch Center for Genetic Engineering, Indonesian National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia.
Marissa AngelinaResearch Center for Pharmaceutical Ingredients and Traditional Medicine, Indonesian National Research and Innovation Agency (BRIN), Serpong 15314, Indonesia.
Yana RubiyanaResearch Center for Genetic Engineering, Indonesian National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia.
Reza AditamaBiochemistry Research Group, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung 40132, Indonesia.
Ratih A NingrumResearch Center for Genetic Engineering, Indonesian National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia.
Andri WardianaResearch Center for Genetic Engineering, Indonesian National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia.
Azzania FibrianiSchool of Life Sciences and Technology, Institut Teknologi Bandung, Bandung 40132, Indonesia.
Bandung Institute of Technology · IDNational Research and Innovation Agency · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 endemic remains a global concern. The search for effective antiviral candidates is still needed to reduce disease risk. However, the availability of high biosafety level laboratory facilities for drug screening is limited in number. To address this issue, a screening system that could be utilized at lower biosafety levels remains essential. This study aimed to develop a novel SARS-CoV-2 main protease (M

Indexed as

COVID-19SARS-CoV-2Antiviral AgentsDimerizationHumansMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsSaquinavirSynthetic BiologyAntiviral AgentsProtease InhibitorsSaquinavirantivirusCOVID-19dimer-based screening systemdrug discoverymain proteaseprotease inhibitor

Identifiers

PMID38316139
PMCPMC10877612
OpenAlexW4391544151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.