Evidence map›Paper›PMID 38315997›Full record

Trial reportAnnals of internal medicine2024

Reducing Care Overuse in Older Patients Using Professional Norms and Accountability : A Cluster Randomized Controlled Trial.

Stephen D Persell, Lucia C Petito, Ji Young Lee, Daniella Meeker, Jason N Doctor, Noah J Goldstein, Craig R Fox, Theresa A Rowe, Jeffrey A Linder, Ryan Chmiel and 2 more

Erratum issued 2 registry-linked trialsAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Annals of internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04289753 nacompletednot on this map

Behavioral Economics Applications to Geriatrics Leveraging EHRs R33 Trial

TypeinterventionalSponsorNorthwestern UniversityRan2020 to 2022Enrolled37,134ConditionsProstate Specific Antigen Screening, Asymptomatic Bacteriuria, Type 2 DiabetesArmsEHR clinical decision support nudges, Brief clinician education
NCT07397260 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Effects of Manually Recorded or Automatically Transmitted Home Blood Pressures With or Without Automated Patient Feedback on Hypertension Care

TypeinterventionalSponsorNorthwestern UniversityRan2026 to 2028Enrolled1,304ConditionsHypertension (HTN)ArmsSelf report of home measured blood pressure via patient EHR portal, Automated feedback about home blood pressure results, Automated Transmission of Remotely Measured Blood Pressure
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Factors Influencing Physician Adherence to Venous Thromboembolism Risk Assessment Model Recommendations: A Best-Worst Scaling.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026
    Article
  3. Overdiagnosis and Overtreatment in Prostate Cancer.Diseases (Basel, Switzerland) · 2025
    Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Stephen D PersellDivision of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago; and Center for Primary Care Innovation, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (S.D.P., J.A.L.).ORCID 0000-0003-2462-1314
Lucia C PetitoDivision of Biostatistics, Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (L.C.P.).ORCID 0000-0002-0156-1219
Ji Young LeeDivision of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (J.Y.L., T.A.R., Y.A.P., T.B.).ORCID 0000-0002-6102-0510
Daniella MeekerYale School of Medicine, New Haven, Connecticut (D.M.).ORCID 0000-0002-1034-7628
Jason N DoctorDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California (J.N.D.).ORCID 0000-0003-3661-8745
Noah J GoldsteinUCLA Anderson School of Management, UCLA Geffen School of Medicine, Los Angeles, California (N.J.G., C.R.F.).
Craig R FoxUCLA Anderson School of Management, UCLA Geffen School of Medicine, Los Angeles, California (N.J.G., C.R.F.).ORCID 0000-0001-9057-112X
Theresa A RoweDivision of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (J.Y.L., T.A.R., Y.A.P., T.B.).
Jeffrey A LinderDivision of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago; and Center for Primary Care Innovation, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (S.D.P., J.A.L.).ORCID 0000-0003-2217-184X
Ryan ChmielInformation Services, Northwestern Memorial HealthCare, Chicago, Illinois (R.C.).
Yaw Amofa PeprahDivision of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (J.Y.L., T.A.R., Y.A.P., T.B.).ORCID 0000-0001-7211-9519
Tiffany BrownDivision of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (J.Y.L., T.A.R., Y.A.P., T.B.).

Funding

Behavioral Economics Applications to Geriatrics Leveraging EHRs (BEAGLE)R33AG057383 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERSELL, STEPHEN · 2019 to 2021
$2.1M
NIA NIH HHS R33 AG057383
6 · The paper itself

Abstract

backgroundEffective strategies are needed to curtail overuse that may lead to harm.

objectiveTo evaluate the effects of clinician decision support redirecting attention to harms and engaging social and reputational concerns on overuse in older primary care patients.

design18-month, single-blind, pragmatic, cluster randomized trial, constrained randomization. (ClinicalTrials.gov: NCT04289753).

setting60 primary care internal medicine, family medicine and geriatrics practices within a health system from 1 September 2020 to 28 February 2022.

participants371 primary care clinicians and their older adult patients from participating practices.

interventionBehavioral science-informed, point-of-care, clinical decision support tools plus brief case-based education addressing the 3 primary clinical outcomes (187 clinicians from 30 clinics) were compared with brief case-based education alone (187 clinicians from 30 clinics). Decision support was designed to increase salience of potential harms, convey social norms, and promote accountability. MEASUREMENTS: Prostate-specific antigen (PSA) testing in men aged 76 years and older without previous prostate cancer, urine testing for nonspecific reasons in women aged 65 years and older, and overtreatment of diabetes with hypoglycemic agents in patients aged 75 years and older and hemoglobin A

resultsAt randomization, mean clinic annual PSA testing, unspecified urine testing, and diabetes overtreatment rates were 24.9, 23.9, and 16.8 per 100 patients, respectively. After 18 months of intervention, the intervention group had lower adjusted difference-in-differences in annual rates of PSA testing (-8.7 [95% CI, -10.2 to -7.1]), unspecified urine testing (-5.5 [CI, -7.0 to -3.6]), and diabetes overtreatment (-1.4 [CI, -2.9 to -0.03]) compared with education only. Safety measures did not show increased emergency care related to urinary tract infections or hyperglycemia. An HbA LIMITATION: A single health system limits generalizability; electronic health data limit ability to differentiate between overtesting and underdocumentation.

conclusionDecision support designed to increase clinicians' attention to possible harms, social norms, and reputational concerns reduced unspecified testing compared with offering traditional case-based education alone. Small decreases in diabetes overtreatment may also result in higher rates of uncontrolled diabetes. PRIMARY FUNDING SOURCE: National Institute on Aging.

Indexed as

Diabetes MellitusProstatic NeoplasmsAgedHumansHypoglycemic AgentsMaleProstate-Specific AntigenSingle-Blind MethodHypoglycemic AgentsProstate-Specific Antigen

Identifiers

PMID38315997
PMCPMC12080469

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.