Evidence map›Paper›PMID 38315959›Full record

Observational studyAmerican journal of respiratory and critical care medicine2024

Accelerated Lung Function Decline and Mucus-Microbe Evolution in Chronic Obstructive Pulmonary Disease.

Oliver W Meldrum, Gavin C Donaldson, Jayanth Kumar Narayana, Fransiskus Xaverius Ivan, Tavleen K Jaggi, Micheál Mac Aogáin, Lydia J Finney, James P Allinson, Jadwiga A Wedzicha, Sanjay H Chotirmall

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  7. Observational
  8. Review
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  11. Review
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  15. Review
  16. Correlation ofInternational journal of chronic obstructive pulmonary disease · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Oliver W MeldrumLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.ORCID 0000-0002-3442-2151
Gavin C DonaldsonNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Jayanth Kumar NarayanaLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Fransiskus Xaverius IvanLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Tavleen K JaggiLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Micheál Mac AogáinLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.ORCID 0000-0002-1726-7700
Lydia J FinneyNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
James P AllinsonNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Jadwiga A WedzichaLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Sanjay H ChotirmallLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.ORCID 0000-0003-0417-7607
Nanyang Technological University · SGImperial College London · GBRoyal Brompton Hospital · GB

Funding

NEW HEPARIN-DEPENDENT PROTEASE INHIBITOR IN HUMAN PLASMAK04HL001079 · NHLBI · WASHINGTON UNIVERSITY · PI TOLLEFSEN, DOUGLAS M · 1985 to 1986
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LKCMedicine-ICL Fellowship 020458-00001LKCMedicine LEARN Grant LEARN008National Heart and Lung Institute (NHLI) Lectureship SGL026/1079National Institute of Health Research (NIHR) Biomedical Research Centre to Imperial College LondonNational Institute of Health Research (NIHR) Biomedical Research Centre to Royal Brompton HospitalNational Medical Research Council MOH-000141National Medical Research Council MOH-000710National Medical Research Council MOH-001356Singapore Ministry of Education under its AcRF Tier 1 Grant RT1/22
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MicrobiotaMucusPulmonary Disease, Chronic ObstructiveSputumAchromobacterAgedAged, 80 and overDisease ProgressionFemaleForced Expiratory VolumeHumansKlebsiellaLongitudinal StudiesMaleMiddle AgedMucin 5ACMucin 5ACMucin-5BCOPDlung function declinemetagenomicsmucusrheology

Identifiers

PMID38315959
PMCPMC11348959
OpenAlexW4391543809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.