Evidence map›Paper›PMID 38315649›Full record

ArticleJournal of agricultural and food chemistry2024

The Promiscuity of Squalene Synthase-Like Enzyme: Dehydrosqualene Synthase, a Natural Squalene Hyperproducer?

Zheng Guan, Yafeng Song, Marcel de Vries, Hjalmar Permentier, Pieter Tepper, Ronald van Merkerk, Rita Setroikromo, Wim J Quax

Open access · hybridAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Zheng GuanDepartment of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.ORCID 0000-0001-8617-8114
Yafeng SongDepartment of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.
Marcel de VriesInterfaculty Mass Spectrometry Center, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.
Hjalmar PermentierInterfaculty Mass Spectrometry Center, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.ORCID 0000-0001-7317-8887
Pieter TepperDepartment of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.
Ronald van MerkerkDepartment of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.
Rita SetroikromoDepartment of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.
Wim J QuaxDepartment of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Groningen9713 AV, The Netherlands.ORCID 0000-0002-5162-9947
University of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dehydrosqualene synthase (CrtM), as a squalene synthase-like enzyme from

Indexed as

Farnesyl-Diphosphate FarnesyltransferaseSqualeneNitric Oxide SynthaseTandem Mass SpectrometryTerpenesdehydrosqualeneFarnesyl-Diphosphate FarnesyltransferaseNitric Oxide SynthaseSqualeneTerpenesCrtMenzyme promiscuitySQSsqualeneterpenoid

Identifiers

PMID38315649
PMCPMC10870770
OpenAlexW4391529411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.