Evidence map›Paper›PMID 38315362›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Production and Purification of Plasmodium Circumsporozoite Protein in Lactococcus lactis.

Mohammad Naghizadeh, Susheel K Singh, Jordan Plieskatt, Ebenezer Addo Ofori, Michael Theisen

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad NaghizadehDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Susheel K SinghBiotherapeutic and Vaccine Research Division, ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India.
Jordan PlieskattDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Ebenezer Addo OforiDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Michael TheisenDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is a vector-borne disease caused by Plasmodium parasites of which Plasmodium falciparum contributed to an estimated 247 million cases worldwide in 2021 (WHO malaria report 2022). The P. falciparum Circumsporozoite protein (PfCSP) covers the surface of the sporozoite which is critical to cell invasion in the human host. PfCSP is the leading pre-erythrocytic vaccine candidate and forms the basis of the RTS'S (Mosquirix

Indexed as

Lactococcus lactisMalariaMalaria, FalciparumMalaria VaccinesAntibodies, ProtozoanHumansPlasmodium falciparumProtozoan ProteinsAntibodies, ProtozoanMalaria VaccinesProtozoan ProteinsCircumsporozoite protein (CSP)CloningLactococcus lactismalariaPlasmodium falciparumPurificationRecombinant protein expression

Identifiers

PMID38315362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.