Evidence map›Paper›PMID 38315035›Full record

ArticlemBio2024

The end of the reign of a "master regulator''? A defect in function of the LasR quorum sensing regulator is a common feature of

Mylène C Trottier, Thays de Oliveira Pereira, Marie-Christine Groleau, Lucas R Hoffman, Ajai A Dandekar, Eric Déziel

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modulation of themBio · 2025
    Article
  9. Article
  10. Review
  11. Comparative genomics ofJournal of bacteriology · 2025
    Article
  12. Article
  13. Article
  14. PqsE adapts the activity of theJournal of bacteriology · 2025
    Article
  15. Article
  16. AvirulentmicroLife · 2025
    Article
  17. Anaeic and tumoic acids, new functionalized fatty acids from marine cyanobacteria, inhibit quorum sensing inMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2025
    Article
  18. Article
  19. The relationship betweenJournal of bacteriology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mylène C TrottierCentre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval, Québec, Canada.ORCID 0009-0002-5849-5686
Thays de Oliveira PereiraCentre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval, Québec, Canada.ORCID 0000-0002-8299-1252
Marie-Christine GroleauCentre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval, Québec, Canada.ORCID 0000-0003-4810-1030
Lucas R HoffmanDepartments of Pediatrics and Microbiology, University of Washington, Seattle, Washington, USA.
Ajai A DandekarDepartments of Medicine and Microbiology, University of Washington, Seattle, Washington, USA.
Eric DézielCentre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval, Québec, Canada.ORCID 0000-0002-4609-0115
Institut National de la Recherche Scientifique · CAUniversity of Washington · US

Funding

Pseudomonas aeruginosa quorum sensingR01GM125714 · NIGMS · UNIVERSITY OF WASHINGTON · PI DANDEKAR, AJAI · 2018 to 2022
$1.6M
Patient-oriented microbiome and advanced culture approaches to identifying the microbial determinants of chronic pediatric diseaseK24HL141669 · NHLBI · UNIVERSITY OF WASHINGTON · PI Lucas R Hoffman · 2018 to 2026
$929k
NHLBI NIH HHS K24 HL141669NIGMS NIH HHS R01 GM125714
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pseudomonas InfectionsQuorum SensingBacterial ProteinsGene Expression Regulation, BacterialHumansPseudomonas aeruginosaTrans-ActivatorsVirulence FactorsBacterial ProteinsTrans-ActivatorsVirulence Factorsadaptive mutationsecologyopportunistic infectionsPseudomonas aeruginosaquorum sensingvirulence regulation

Identifiers

PMID38315035
PMCPMC10936206
OpenAlexW4391556214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.