Evidence map›Paper›PMID 38314621›Full record

ReviewBiochemical Society transactions2024

Atypical RhoUV GTPases in development and disease.

Stephanie Woo, Leesa Strasser

Open access · hybridAbstract readReview
In one paragraph

Review in Biochemical Society transactions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephanie WooDepartment of Molecular Cell Biology, University of California, Merced, CA, U.S.A.ORCID 0000-0002-1238-8167
Leesa StrasserDepartment of Molecular Cell Biology, University of California, Merced, CA, U.S.A.
University of California, Merced · US

Funding

Determining the role of cellular forces in endoderm differentiation and developmentR21HD107313 · NICHD · UNIVERSITY OF CALIFORNIA, MERCED · PI WOO, STEPHANIE · 2022 to 2023
$327k
In vivo analysis of gastrointestinal epithelium morphogenesisR03DK106358 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOO, STEPHANIE · 2015 to 2016
$158k
NICHD NIH HHS R21 HD107313NIDDK NIH HHS R03 DK106358
6 · The paper itself

Abstract

RhoU and RhoV are members of the Rho family of small GTPases that comprise their own subfamily. RhoUV GTPases are classified as atypical due to the kinetics of their GTP/GDP binding cycles. They also possess unique N- and C-termini that regulate their subcellular localization and activity. RhoU and RhoV have been linked to cytoskeletal regulation, cell adhesion, and cell migration. They each exhibit distinct expression patterns during embryonic development and diseases such as cancer metastasis, suggesting they have specialized functions. In this review, we will discuss the known functions of RhoU and RhoV, with a focus on their roles in early development, organogenesis, and disease.

Indexed as

GTP-Binding Proteinsrho GTP-Binding ProteinsCell AdhesionSignal TransductionGTP-Binding Proteinsrho GTP-Binding ProteinscancerembryogenesisEMTRho GTPasesRhoURhoV

Identifiers

PMID38314621
PMCPMC10903452
OpenAlexW4391533889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.