Evidence map›Paper›PMID 38314602›Full record

ReviewCurrent protein & peptide science2024

Combating Aminoglycoside Resistance: From Structural and Functional Characterisation to Therapeutic Challenges with RKAAT.

Sarah Oluwatobi Otun, Richard Graca, Ikechukwu Achilonu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current protein & peptide science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. CombatingFrontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarah Oluwatobi OtunDepartment of Molecular and Cell Biology, Protein Structure-function Unit, University of Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-5408-695X
Richard GracaDepartment of Molecular and Cell Biology, Protein Structure-function Unit, University of Witwatersrand, Johannesburg, South Africa.
Ikechukwu AchilonuDepartment of Molecular and Cell Biology, Protein Structure-function Unit, University of Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-8658-956X
University of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A comprehensive knowledge of aminoglycoside-modifying enzymes (AMEs) and their role in bacterial resistance mechanisms is urgently required due to the rising incidence of antibiotic resistance, particularly in

Indexed as

AminoglycosidesAnti-Bacterial AgentsKlebsiella pneumoniaeBacterial ProteinsDrug Resistance, BacterialHumansKlebsiella InfectionsMicrobial Sensitivity TestsNucleotidyltransferasesRecombinant ProteinsAminoglycosidesAnti-Bacterial AgentsBacterial ProteinsNucleotidyltransferasesRecombinant Proteins(3”) (9) adenylyl transferase (RKAAT).Adenylyl transferaseaminoglycoside antibioticsantibiotic resistancehealthcare-associated infectionsKlebsiella pneumoniaeKlebsiella pneumoniae Aminoglycosiderecombinant

Identifiers

PMID38314602
OpenAlexW4391522185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.