Evidence map›Paper›PMID 38314258›Full record

ArticleEmergency and critical care medicine2023

COVID-19 and cardiovascular complications: updates of emergency medicine.

Jianli Zhao, Yaoli Xie, Zhijun Meng, Caihong Liu, Yalin Wu, Fujie Zhao, Xinliang Ma, Theodore A Christopher, Bernard J Lopez, Yajing Wang

Open access · diamondAbstract read
In one paragraph

Article in Emergency and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jianli ZhaoEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Yaoli XieEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Zhijun MengEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Caihong LiuEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Yalin WuDepartment of Biomedical Engineering, University of Alabama at Birmingham, AL, USA.
Fujie ZhaoDepartment of Biomedical Engineering, University of Alabama at Birmingham, AL, USA.
Xinliang MaEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Theodore A ChristopherEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Bernard J LopezEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Yajing WangEmergency Medicine Department, Thomas Jefferson University, Philadelphia, PA, USA.
Thomas Jefferson University · USUniversity of Alabama at Birmingham · US

Funding

Targeting Adiponectin for Cardioprotection in the Ischemic HeartR01HL096686 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI MA, XIN-LIANG, WANG, YAJING · 2010 to 2024
$4.7M
Cav-3 in Diabetic Myocardial Injury Following Ischemia/ReperfusionR01HL123404 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI MA, XIN-LIANG · 2015 to 2023
$2.7M
Dysregulated Adiponectin Transmembrane Signaling in Diabetic CoronaryVascular Injury and Heart FailureR01HL157495 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, YAJING · 2022 to 2025
$2.3M
Critical Role of Small Extracellular Vesicles in Diabetic Coronary VascularDysfunction and Diabetic Ischemic Heart Failure effortsR01HL158612 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, YAJING · 2021 to 2024
$1.5M
Cav-3 in Diabetic Myocardial Injury Following Ischemia/ReperfusionR56HL123404 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI MA, XIN-LIANG · 2014 to 2014
$388k
NHLBI NIH HHS R01 HL096686NHLBI NIH HHS R01 HL123404NHLBI NIH HHS R01 HL157495NHLBI NIH HHS R01 HL158612NHLBI NIH HHS R56 HL123404
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV-2 variants, has become a global pandemic resulting in significant morbidity and mortality. Severe cases of COVID-19 are characterized by hypoxemia, hyper-inflammation, cytokine storm in lung. Clinical studies have reported an association between COVID-19 and cardiovascular disease (CVD). Patients with CVD tend to develop severe symptoms and mortality if contracted COVID-19 with further elevations of cardiac injury biomarkers. Furthermore, COVID-19 itself can induce and promoted CVD development, including myocarditis, arrhythmia, acute coronary syndrome, cardiogenic shock, and venous thromboembolism. Although the direct etiology of SARS-CoV-2 induced cardiac injury remains unknown and under-investigated, it is suspected that it is related to myocarditis, cytokine-mediated injury, microvascular injury, and stress-related cardiomyopathy. Despite vaccinations having provided the most effective approach to reducing mortality overall, an adapted treatment paradigm and regular monitoring of cardiac injury biomarkers is critical for improving outcomes in vulnerable populations at risk for severe COVID-19. In this review, we focus on the latest progress in clinic and research on the cardiovascular complications of COVID-19 and provide a perspective of treating cardiac complications deriving from COVID-19 in Emergency Medicine.

Indexed as

Cardiovascular diseaseCOVID-19Emergency MedicineSARS- CoV-2

Identifiers

PMID38314258
PMCPMC10836842
OpenAlexW4379056840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.