Evidence map›Paper›PMID 38313824›Full record

ReviewRegenerative biomaterials2024

Recent progress in functional metal-organic frameworks for bio-medical application.

Wenwen Chai, Xiaochen Chen, Jing Liu, Liyan Zhang, Chunyu Liu, Li Li, John Robert Honiball, Haobo Pan, Xu Cui, Deping Wang

Open access · goldAbstract readReview
In one paragraph

Review in Regenerative biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Hierarchical Functionalisation of UiO-66(Zr)-NHNanomaterials (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Fabrication of3 Biotech · 2025
    Article
  14. MOF-Based Bioelectronic Supercapacitors.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  15. Review
  16. Review
  17. Article
  18. Smart responsiveFrontiers in bioengineering and biotechnology · 2024
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Wenwen ChaiSchool of Materials Science and Engineering, Tongji University, Shanghai 201804, China.
Xiaochen ChenSchool of Materials Science and Engineering, Tongji University, Shanghai 201804, China.
Jing LiuSchool of Materials Science and Engineering, Tongji University, Shanghai 201804, China.
Liyan ZhangShenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Chunyu LiuShenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Li LiDepartment of Orthopaedics & Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
John Robert HoniballDepartment of Orthopaedics & Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Haobo PanShenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Xu CuiShenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Deping WangSchool of Materials Science and Engineering, Tongji University, Shanghai 201804, China.ORCID https://orcid.org/0000-0003-4246-5757
Chinese Academy of Sciences · CNTongji University · CNChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal-organic frameworks (MOFs) have a high specific surface area, adjustable pores and can be used to obtain functional porous materials with diverse and well-ordered structures through coordination and self-assembly, which has intrigued wide interest in a broad range of disciplines. In the arena of biomedical engineering, the functionalized modification of MOFs has produced drug carriers with excellent dispersion and functionalities such as target delivery and response release, with promising applications in bio-detection, disease therapy, tissue healing, and other areas. This review summarizes the present state of research on the functionalization of MOFs by physical binding or chemical cross-linking of small molecules, polymers, biomacromolecules, and hydrogels and evaluates the role and approach of MOFs functionalization in boosting the reactivity of materials. On this basis, research on the application of functionalized MOFs composites in biomedical engineering fields such as drug delivery, tissue repair, disease treatment, bio-detection and imaging is surveyed, and the development trend and application prospects of functionalized MOFs as an important new class of biomedical materials in the biomedical field are anticipated, which may provide some inspiration and reference for further development of MOF for bio-medical applications.

Indexed as

disease treatmentfunctionalizationmetal–organic frameworksporoustissue repair

Identifiers

PMID38313824
PMCPMC10838214
OpenAlexW4390140721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.