Evidence map›Paper›PMID 38313794›Full record

ArticlePharmacogenomics and personalized medicine2024

The Impact of Opioid Receptor Gene Polymorphism on Fentanyl and Alfentanil's Analgesic Effects in the Pediatric Perioperative Period.

Jelena Lilic, Vesna G Marjanovic, Ivana Budic, Nikola Stefanovic, Dragana Stokanovic, Goran T Marjanovic, Tatjana Jevtovic-Stoimenov, Mladjan Golubovic, Maja Zecevic, Radmila Velickovic-Radovanovic

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. The Rise of Fentanyl: Molecular Aspects and Forensic Investigations.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jelena LilicClinic for Anesthesia and Intensive Therapy, University Clinical Centre Nis, Nis, Serbia.ORCID 0009-0009-3334-4823
Vesna G MarjanovicClinic for Anesthesia and Intensive Therapy, University Clinical Centre Nis, Nis, Serbia.ORCID 0000-0003-4435-9309
Ivana BudicClinic for Anesthesia and Intensive Therapy, University Clinical Centre Nis, Nis, Serbia.ORCID 0000-0001-5364-924X
Nikola StefanovicDepartment of Pharmacy, Faculty of Medicine, University of Nis, Nis, Serbia.ORCID 0000-0003-2599-7508
Dragana StokanovicDepartment of Pharmacology with Toxicology, Faculty of Medicine, University of Nis, Nis, Serbia.
Goran T MarjanovicDepartment of Immunology, Faculty of Medicine, University of Nis, Nis, Serbia.
Tatjana Jevtovic-StoimenovInstitute of Biochemistry, Faculty of Medicine, University of Nis, Nis, Serbia.
Mladjan GolubovicDepartment of Surgery and Anesthesiology with Reanimatology, Faculty of Medicine, University of Nis, Nis, Serbia.
Maja ZecevicClinic of Pediatric Surgery, University Clinical Centre Nis, Nis, Serbia.
Radmila Velickovic-RadovanovicDepartment of Pharmacology with Toxicology, Faculty of Medicine, University of Nis, Nis, Serbia.ORCID 0009-0005-6417-9673
University of Nis · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The polymorphism of the gene coding mu-opioid receptor ( Methods: This prospective study analyzed 110 pediatric patients, after plastic or orthopedic surgery, who were genotyped and randomly assigned to receive fentanyl or alfentanil. Postoperative pain was rated using Numerical Rating Scale (0-10). All the patients were genotyped for Results: School children under the age of 11 with the Discussion:

Indexed as

childrenopioidOPRM1painpolymorphism

Identifiers

PMID38313794
PMCPMC10838050
OpenAlexW4391363410

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.