Evidence map›Paper›PMID 38313533›Full record

ArticleACS omega2024

Streamlined Chemo-Enzymatic Synthesis of Molnupiravir via Lipase Catalyst.

Khawlhring Rosangzuala, Ravinder Reddy Patlolla, Asif Shaikh, Kethavath Anjali Priya Naik, Gajjala Raveena, Manjula Nemali, Mohana Krishna Reddy Mudiam, Linga Banoth

Abstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khawlhring RosangzualaAcademy of Scientific and Innovative Research, Ghaziabad 201002, India.
Ravinder Reddy PatlollaAcademy of Scientific and Innovative Research, Ghaziabad 201002, India.
Asif ShaikhAcademy of Scientific and Innovative Research, Ghaziabad 201002, India.
Kethavath Anjali Priya NaikOrganic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Gajjala RaveenaOrganic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Manjula NemaliOrganic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Mohana Krishna Reddy MudiamInstitute of Pesticide Formulation Technology (IPFT), Sector-20, Udyog Vihar, Gurugram, Haryana 122016, India.
Linga BanothOrganic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.ORCID https://orcid.org/0000-0003-2012-6543

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An enzymatic approach for the synthesis of Molnupiravir has been developed using immobilized lipase as a biocatalyst. This method involves a concise process of the regioselective esterification of uridine with isobutyric anhydride using Lipase (Addzyme-011). This efficient route gets 97% conversion of uridine

Identifiers

PMID38313533
PMCPMC10831972

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.