Evidence map›Paper›PMID 38313457›Full record

ArticleWorld journal of gastrointestinal endoscopy2024

Propofol sedation in routine endoscopy: A case series comparing target controlled infusion

Riad Sarraj, Lorenz Theiler, Nima Vakilzadeh, Niklas Krupka, Reiner Wiest

Open access · diamondAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Riad SarrajDepartment of Visceral Surgery and Medicine, Inselspital University Hospital, Bern 3010, Switzerland. riad.sarraj@insel.ch.
Lorenz TheilerClinic for Anesthesia, Perioperative, Emergency & Intensive Care Medicine, Kantonsspital Aarau, Aarau 5001, Switzerland.
Nima VakilzadehDepartment of Nephrology and Hypertension, University Hospital Lausanne, Lausanne 1011, Switzerland.
Niklas KrupkaDepartment of Visceral Surgery and Medicine, Inselspital University Hospital, Bern 3010, Switzerland.
Reiner WiestDepartment of Visceral Surgery and Medicine, Inselspital University Hospital, Bern 3010, Switzerland.
Kantonsspital Aarau · CHUniversity Hospital of Bern · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies have addressed safety and effectiveness of non-anaesthesiologist propofol sedation (NAPS) for gastrointestinal (GI) endoscopy Target controlled infusion (TCI) is claimed to provide an optimal sedation regimen by avoiding under- or oversedation.

aimTo assess safety and performance of propofol TCI sedation in comparison with nurse-administered bolus-sedation.

methodsFouty-five patients undergoing endoscopy under TCI propofol sedation were prospectively included from November 2016 to May 2017 and compared to 87 patients retrospectively included that underwent endoscopy with NAPS. Patients were matched for age and endoscopic procedure. We recorded time of sedation and endoscopy, dosage of medication and adverse events.

resultsThere was a significant reduction in dose per time of propofol administered in the TCI group, compared to the NAPS group (8.2 ± 2.7 mg/min

conclusionThis study indicates that sedation using TCI for GI endoscopy reduces the dose of propofol necessary per minute of endoscopy. This may translate into less adverse events. However, further and randomized trials need to confirm this trend.

Indexed as

Adverse eventEndoscopyNon-anaesthesiologist propofol sedationPropofolSedationTarget controlled infusion

Identifiers

PMID38313457
PMCPMC10835478
OpenAlexW4390864810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.