Evidence map›Paper›PMID 38313298›Full record

ArticleResearch square2024

Autoantibodies neutralizing GM-CSF in HIV-negative Colombian patients infected with Cryptococcus gattii and C. neoformans.

Carlos A Arango-Franco, Julián Rojas, Carolina Firacative, Clara Inés Agudelo, José Luis Franco, Jean-Laurent Casanova, Anne Puel, Jairo Lizarazo, Elizabeth Castañeda, Andrés A Arias

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Carlos A Arango-FrancoUniversity of Antioquia (UdeA).
Julián RojasUniversity of Antioquia (UdeA).
Carolina FiracativeUniversity del Rosario.
Clara Inés AgudeloInstituto Nacional de Salud.
José Luis FrancoUniversity of Antioquia (UdeA).
Jean-Laurent CasanovaINSERM U1163, Necker Hospital for Sick Children.
Anne PuelINSERM U1163, Necker Hospital for Sick Children.
Jairo LizarazoUniversity of Pamplona.
Elizabeth CastañedaInstituto Nacional de Salud.
Andrés A AriasUniversity of Antioquia (UdeA).
Inserm · FRUniversidad del Rosario · COUniversity of Pamplona · CO

Funding

Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasisR01AI127564 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Jean-Laurent Casanova · 2017 to 2026
$4.8M
NCATS NIH HHS UL1 TR001866NIAID NIH HHS R01 AI127564
6 · The paper itself

Abstract

Background: Cryptococcosis is a life-threatening disease caused by Methods: We reviewed clinical and laboratory records and assessed the presence of neutralizing auto-Abs in 30 HIV (-) adults presenting cryptococcosis (13 by Results: We detected auto-Abs neutralizing GM-CSF in the plasma of 9 out of 13 (69%) patients infected with Conclusions: We report ten Colombian patients with cryptococcosis due to auto-Abs neutralizing GM-CSF. Nine of the ten patients were infected with

Indexed as

anti-cytokine autoantibodiesautoantibodies (auto-Abs) neutralizing GM-CSFCryptococcosisCryptococcus gattiiCryptococcus neoformansGM-CSF autoantibodiesGranulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)HIV-negative patientshuman immunodeficiency virus (HIV)Mycobacterium tuberculosis (Mtb)Pulmonary tuberculosis (Tb)

Identifiers

PMID38313298
PMCPMC10836105
OpenAlexW4391015544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.