Evidence map›Paper›PMID 38313225›Full record

ArticleCurrent research in food science2024

Naringin ameliorates obesity via stimulating adipose thermogenesis and browning, and modulating gut microbiota in diet-induced obese mice.

Xiaoping Li, Zhao Yao, Xinyue Qi, JinLing Cui, Yuliang Zhou, Yihong Tan, Xiaojun Huang, Hui Ye

Open access · goldAbstract read
In one paragraph

Article in Current research in food science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  5. Frontiers in microbiology · 2026
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xiaoping LiCollege of Culinary Science, Sichuan Tourism University, Chengdu, 610100, China.
Zhao YaoSchool of Health Industry, Sichuan Tourism University, Chengdu, 610100, China.
Xinyue QiSchool of Chemistry, Chemical Engineering, and Biotechnology, Nanyang Technological University, Singapore, 637371.
JinLing CuiCollege of Culinary Science, Sichuan Tourism University, Chengdu, 610100, China.
Yuliang ZhouSchool of Chemistry, Chemical Engineering, and Biotechnology, Nanyang Technological University, Singapore, 637371.
Yihong TanSchool of Chemistry, Chemical Engineering, and Biotechnology, Nanyang Technological University, Singapore, 637371.
Xiaojun HuangState Key Laboratory of Food Science and Resources, China-Canada Joint Lab of Food Science and Technology (Nanchang), Nanchang University, 235 Nanjing East Road, Nanchang, 330047, China.
Hui YeSchool of Chemistry, Chemical Engineering, and Biotechnology, Nanyang Technological University, Singapore, 637371.
Nanyang Technological University · SGSichuan Tourism University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naringin, a natural flavanone primarily found in citrus fruits, has garnered increased attention due to its recognized antioxidative, anti-inflammatory, and cardioprotective attributes. However, the functions of naringin in regulating energy expenditure are poorly understood. In the present study, we observed that twelve weeks of naringin supplementation substantially reshaped the metabolic profile of high-fat diet (HFD)-fed mice, by inhibiting body weight gain, reducing liver weight, and altering body compositions. Notably, naringin exhibited a remarkable capacity to augment whole-body energy expenditure of the tested mice by enhancing the thermogenic activity of brown adipose tissue (BAT) and stimulating browning of inguinal white adipose tissue (iWAT). Furthermore, our results showed naringin supplementation modified gut microbiota composition, specifically increasing the abundance of

Indexed as

Fat browningFecal metabolitesGut microbiotaNaringinObesityThermogenesis

Identifiers

PMID38313225
PMCPMC10835601
OpenAlexW4390966584

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.