Evidence map›Paper›PMID 38312848›Full record

ReviewTherapeutic advances in infectious disease

Challenges and advances in the medical treatment of granulomatous amebic encephalitis.

Natasha Spottiswoode, Julia C Haston, Natasha W Hanners, Katherine Gruenberg, Annie Kim, Joseph L DeRisi, Michael R Wilson

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  12. Article
  13. Drug susceptibility of a clinical isolate ofAntimicrobial agents and chemotherapy · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Fatal amoebic meningoencephalitis caused byFrontiers in veterinary science · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Natasha SpottiswoodeDivision of Infectious Diseases, University of California San Francisco, San Francisco, CA, USA.
Julia C HastonDivision of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Natasha W HannersDivision of Pediatric Infectious Diseases, University of Texas Southwestern, Dallas, TX, USA.
Katherine GruenbergDepartment of Clinical Pharmacy, University of California San Francisco School of Pharmacy, San Francisco, CA, USA.ORCID https://orcid.org/0000-0003-2552-353X
Annie KimDepartment of Clinical Pharmacy, Zuckerberg San Francisco General, San Francisco, CA, USA.
Joseph L DeRisiDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.
Michael R WilsonWeill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA 94143, USA.ORCID https://orcid.org/0000-0002-8705-5084
University of California, San Francisco · USCenters for Disease Control and Prevention · USSan Francisco General Hospital · USThe University of Texas Southwestern Medical Center · US

Funding

BIOLOGY OF INFECTIOUS DISEASES TRAINING PROGRAMT32AI007641 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY · 2000 to 2026
$6.9M
NIAID NIH HHS T32 AI007641
6 · The paper itself

Abstract

Granulomatous amebic encephalitis, caused by the free-living amebae

Indexed as

AcanthamoebaamebaBalamuthiadrug repurposingencephalitis

Identifiers

PMID38312848
PMCPMC10838035
OpenAlexW4391515983

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.