Evidence map›Paper›PMID 38312801›Full record

ArticleMaterials today. Bio2024

Nanotexture and crystal phase regulation for synergistic enhancement in re-endothelialization on medical pure titanium surface.

Jing Zhang, Kai Ren, Jingru Qiu, Baolan Chen, Weixun Duan, Jincheng Liu, Guiling Li, Donghai Li

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jing ZhangAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shenzhen Research Institute of Shandong University, Shandong University, Jinan, Shandong, PR China.
Kai RenDepartment of Cardiovascular Surgery, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, PR China.
Jingru QiuDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China.
Baolan ChenAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shenzhen Research Institute of Shandong University, Shandong University, Jinan, Shandong, PR China.
Weixun DuanDepartment of Cardiovascular Surgery, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, PR China.
Jincheng LiuDepartment of Cardiovascular Surgery, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, PR China.
Guiling LiAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shenzhen Research Institute of Shandong University, Shandong University, Jinan, Shandong, PR China.
Donghai LiAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shenzhen Research Institute of Shandong University, Shandong University, Jinan, Shandong, PR China.
Shandong University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Re-endothelialization has been recognized as a promising strategy to address the tissue hyperplasia and subsequent restenosis which are major complications associated with vascular implant/interventional titanium devices. However, the uncontrollable over-proliferation of smooth muscle cells (SMCs) limits the clinical application of numerous modified strategies. Herein, a novel modified strategy involving with a two-step anodic oxidation and annealing treatment was proposed to achieve rapid re-endothelialization function regulated by regular honeycomb nanotexture and specific anatase phase on the titanium surface. Theoretical calculation revealed that the presence of nanotexture reduced the polar component of surface energy, while the generation of anatase significantly enhanced the polar component and total surface energy. Meanwhile, the modified surface with regular nanotexture and anatase phase produced positive effect on the expression of CD31, VE-Cadherin and down-regulated α-SMA proteins expression, indicating excellent capacity of pro-endothelial regeneration and inhibition of SMCs proliferation and migration. One-month

Indexed as

Anatase phaseCompetitive adhesion of ECs and SMCsEndothelializationPure titaniumTiO2 honeycomb nanotexture

Identifiers

PMID38312801
PMCPMC10835003
OpenAlexW4391054019

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.