Evidence map›Paper›PMID 38312505›Full record

ArticleJournal of pain research2024

Postoperative MRI Findings Following PELD and Their Correlations with Clinical Prognosis are Investigated by Injecting Contrast into Annulus Fibrosus Intraoperatively.

Jinhui Bu, Zhenfei Wang, Chao Ma, Juan Gao, Guangpu Liu, Libo Pang, Bo He, Minghui Dong, Quan Zhang, Yan Lei and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of pain research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Jinhui Bu *Xuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.
Zhenfei Wang *Department of Orthopedic Surgery, Xuzhou Central Hospital, Xuzhou, People's Republic of China.
Chao MaXuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.
Juan GaoDepartment of Orthopedic Surgery, Xuzhou Central Hospital, Xuzhou, People's Republic of China.
Guangpu LiuDepartment of Orthopedic Surgery, Xuzhou Central Hospital, Xuzhou, People's Republic of China.
Libo PangDepartment of Orthopedic Surgery, Xuzhou Central Hospital, Xuzhou, People's Republic of China.
Bo HeXuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.
Minghui DongXuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.
Quan ZhangXuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.
Yan LeiXuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.ORCID 0000-0003-4492-7353
Long XuDepartment of Orthopedic Surgery, Xuzhou Central Hospital, Xuzhou, People's Republic of China.
Sen HuangXuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.
Yuming LiDepartment of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-9223-0038
Guangwang LiuXuzhou Clinical School of Xuzhou Medical University, Xuzhou, People's Republic of China.
Xuzhou Medical College · CNXuzhou Central Hospital · CNBoston Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To validate whether a residual mass demonstrated on early postoperative MR after percutaneous endoscopic lumbar discectomy (PELD) is indeed an intraoperatively retained annulus fibrosus, and explore the correlation between imaging changes in the residual mass and clinical prognosis of patients. Methods: A prospective study of 118 patients were included. During surgery, a contrast medium, Gadopentetate Dimeglumine, was injected around the ruptured annulus fibrosus. The intensity of the T2 signal, the size of the remaining mass (SR), and the cross-sectional area of the spinal canal (SCSA), VAS, and ODI were assessed at preoperative, 1-h (7-day), 6-month, and 12-month postoperative intervals. Based on VAS at 7 days post-surgery, patients were classified into either a non-remission group (Group A, VAS > 3) or a remission group (Group B, VAS ≤ 3). Results: Six patients who developed recurrent LDH were excluded. A residual mass was detected on MRI 1 h after surgery in 94.6% (106/112). During one year of follow-up, 90.1% (101/112) of the patients displayed fibrous annulus remodeling, although 68.7% (77/112) still exhibited herniation. Significant differences were found in the ODI between Groups A and B one week after surgery (p < 0.001). However, no significant differences were observed in T2 signal intensity, SR, and SCSA at 1-h, 6-month and 12-month post-surgery (p > 0.05) between the two groups. In a multiple linear regression analysis, early postoperative ODI changes were associated with T2 signal (B = -10.22, sig < 0.05), long-term changes were associated with alterations in SR (B = 5.63, sig < 0.05) and SCSA (B = -0.13, sig < 0.05). Conclusion: The residual mass observed in early postoperative MR images after PELD was the retained annulus fibrosus intraoperatively. Short-term changes in clinical symptoms after PELD were linked to T2 signal intensity, while long-term changes were associated with changes in SR and SCSA.

Indexed as

contrast mediumremodeling of fibrous annulusresidual massspinal endoscopy

Identifiers

PMID38312505
PMCPMC10838106
OpenAlexW4391363890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.