Evidence map›Paper›PMID 38312113›Full record

ArticleMedical devices (Auckland, N.Z.)2024

Non Clinical Model to Assess the Mechanism of Action of a Combined Hyaluronic Acid, Chondroitin Sulfate and Calcium Chloride: HA+CS+CaCl

Laura Brambilla, Valeria Frangione, Marisa Meloni

Open access · goldAbstract read
In one paragraph

Article in Medical devices (Auckland, N.Z.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Laura BrambillaVitroScreen, in vitro Research Laboratory, Milan, Italy.
Valeria FrangioneIBSA Institut Biochimique SA, Pambio-Noranco, Switzerland.ORCID 0000-0003-0465-8953
Marisa MeloniVitroScreen, in vitro Research Laboratory, Milan, Italy.ORCID 0000-0001-6170-1001
Vitrociset (Italy) · ITIBSA Institut Biochimique (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Medical Device Regulation (EU) 2017/745 requires the principal mode of action (MoA) to be demonstrated by experimental data. The MoA of Ialuril Methods: Three experimental designs; i) Results: No significant differences were observed in bacterial viability for both the Conclusion: The results support the capacity of HA+CS+CaCl

Indexed as

anti-bacterial adhesionchondroitin sulphateE. coli biofilmE. coli UPECfilm forming propertieshyaluronic acidreconstructed 3D human bladder epitheliumrecurrent cystitisurinary tract infections

Identifiers

PMID38312113
PMCPMC10838052
OpenAlexW4391363340

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.