ArticleChild psychiatry and human development2025
The Association of Quality of Life with Psychosocial Factors in Adolescents with Tourette Syndrome.
Article in Child psychiatry and human development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Systematic Literature Review on Public Health Impacts of Persistent Tic Disorders: Education and Employment.Clinical child and family psychology review · 2026Pooled it
- Structural and functional alterations in the brain gray matter among Tourette syndrome patients: a multimodal meta-analysis of fMRI and VBM studies.Journal of neurology · 2025Pooled it
- Tourette syndrome.Nature reviews. Disease primers · 2026Review
- Parent Emotion Socialization Behaviors and Adolescent Psychological Symptoms in Families Impacted by Tourette Syndrome.Research on child and adolescent psychopathology · 2026Article
- Knowledge, Attitudes, and Practices of Caregivers of Children with Tic Disorders Regarding the Traditional Chinese Medicine Diagnosis and Treatment of the Condition.Journal of multidisciplinary healthcare · 2026Article
- Tic severity and quality of life in children with tic disorders: the chain mediating effects of stigma and anxiety.Frontiers in psychiatry · 2026Article
- The Association Between Depression and Tourette Syndrome: A Bibliometric Analysis of Research Hotspots and Emerging Trends from 2001 to 2025.Pediatric health, medicine and therapeutics · 2026Article
- Patient Perspectives on Tic-Related Impairment: A Qualitative Examination.Neurology. Clinical practice · 2025Article
- Growing up with tic disorders: an Italian survey on quality of life and access to care.Frontiers in psychiatry · 2025Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Individuals with Tourette syndrome (TS) have poorer quality of life (QoL) than their peers, yet factors contributing to poor QoL in this population remain unclear. Research to date has predominantly focused on the impact of tics and psychiatric symptoms on QoL in TS samples. The aim of this cross-sectional, multi-informant study was to identify psychosocial variables that may impact adolescent QoL in TS. Thirty-eight adolescents aged 13 to 17 with TS and 28 age-matched controls participated with a caregiver. No group differences were found on QoL, although the TS group reported reduced QoL compared to population normative data. In the TS group, reduced QoL was associated with lower self-esteem, poorer family functioning, higher stress, and greater depression and anxiety; QoL was unrelated to tic severity. In regression analyses, after adjusting for covariates, family functioning was the strongest predictor of QoL. These results emphasize the need to further explore the influence of psychosocial factors, particularly family functioning, on QoL in adolescents with TS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.