Evidence map›Paper›PMID 38311543›Full record

ArticleTrends in cancer2024

Sweet dreams: glycosylation controls tumor cell dormancy.

Erin Bresnahan, Jose Javier Bravo-Cordero

Open access · greenAbstract read
In one paragraph

Article in Trends in cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Erin BresnahanDepartment of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, NY, USA.
Jose Javier Bravo-CorderoDepartment of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, NY, USA. Electronic address: josejavier.bravo-cordero@mssm.edu.
Icahn School of Medicine at Mount Sinai · US

Funding

THE TISCH CANCER INSTITUTE - CANCER CENTER SUPPORT GRANTP30CA196521 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ramon E Parsons · 2015 to 2026
$35.4M
TRAINING PROGRAM IN CANCER THERAPYT32CA078207 · NCI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI James J Manfredi · 1999 to 2026
$11.6M
Defining the role of type III collagen and the collagen-binding receptor DDR1 in metastatic dormancyR01CA244780 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRAVO-CORDERO, JOSE JAVIER · 2020 to 2024
$1.9M
Intersectional genetics-based biosensors for dormant cancer cellsR61CA278402 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRAVO-CORDERO, JOSE JAVIER · 2023 to 2025
$706k
Recording the natural history of cancer progression using a Crainbow model of HER2+ cancerR03CA270679 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRAVO-CORDERO, JOSE JAVIER · 2022 to 2023
$182k
NCI NIH HHS P30 CA196521NCI NIH HHS R01 CA244780NCI NIH HHS R03 CA270679NCI NIH HHS R61 CA278402NCI NIH HHS T32 CA078207
6 · The paper itself

Abstract

In a recent study in Cancer Cell, Sreekumar et al. used therapy-associated breast cancer mouse models as well as in vitro dormancy models to identify extracellular matrix (ECM)-related tumor cell-autonomous mechanisms of dormancy in residual tumor cells (RTCs). The study reveals an important role of the glycosylation of proteoglycans in sustaining dormancy and opens the door to leverage this biology to eliminate RTCs and prevent recurrence.

Indexed as

Extracellular MatrixAnimalsGlycosylationMicedormancyextracellular matrixglycosylationmetastasis

Identifiers

PMID38311543
PMCPMC10939740
OpenAlexW4391507836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.