Evidence map›Paper›PMID 38311493›Full record

ArticleTrends in parasitology2024

Sex in a dish: high-efficiency Toxoplasma pre-sexual development.

Nicole D Hryckowian, Laura J Knoll

Open access · greenAbstract read
In one paragraph

Article in Trends in parasitology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicole D HryckowianDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.
Laura J KnollDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: ljknoll@wisc.edu.
University of Wisconsin–Madison · US

Funding

Sexual Development of Toxoplasma in Feline Intestinal OrganoidsR01AI144016 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KNOLL, LAURA J · 2019 to 2023
$1.9M
Mechanistic analysis of Toxoplasma gondii sexual development in tissue culture and mouse modelsF32AI172084 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIS, NICOLE MARIE · 2022 to 2024
$214k
NIAID NIH HHS F32 AI172084NIAID NIH HHS R01 AI144016
6 · The paper itself

Abstract

Antunes et al. successfully grew cat-restricted stages of Toxoplasma gondii in cell culture by targeting parasite epigenetics and transcription factors. The highlight of this report is how efficiently parasites convert to these pre-sexual stages. Their work is an important step toward achieving feline-free recapitulation of the T. gondii sexual cycle.

Indexed as

ParasitesToxoplasmaAnimalsCatsSexual DevelopmentApiAP2life stage transitionmerozoiteToxoplasma gondii

Identifiers

PMID38311493
PMCPMC10939770
OpenAlexW4391507053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.