ReviewHearing research2024
Neural Fluctuation Contrast as a Code for Complex Sounds: The Role and Control of Peripheral Nonlinearities.
Review in Hearing research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Formant-frequency encoding in the inferior colliculus of awake rabbit: Physiological and model responses.Hearing research · 2026Article
- Timbre Encoding in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Humans can use positive and negative spectrotemporal correlations to detect rising and falling pitch.Nature human behaviour · 2026Article
- Modeling auditory enhancement: Efferent control of cochlear gain can explain level dependence and effects of hearing loss.The Journal of the Acoustical Society of America · 2026Article
- The Effects of Broadband Elicitor Duration on Transient-Evoked Otoacoustic Emissions and a Psychoacoustic Measure of Gain Reduction.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Chirp sensitivity and vowel coding in the inferior colliculus.Hearing research · 2025Article
- Cues for tone-in-noise detection: Evidence from constant-stimuli and adaptive approaches.The Journal of the Acoustical Society of America · 2025Article
- Mechanisms of Tone-in-Noise Encoding in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Profile analysis in listeners with normal and elevated audiometric thresholds: Behavioral and modeling results.The Journal of the Acoustical Society of America · 2024Article
- Limitations on Temporal Processing by Cochlear Implant Users: A Compilation of Viewpoints.Trends in hearingReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The nonlinearities of the inner ear are often considered to be obstacles that the central nervous system has to overcome to decode neural responses to sounds. This review describes how peripheral nonlinearities, such as saturation of the inner-hair-cell response and of the IHC-auditory-nerve synapse, are instead beneficial to the neural encoding of complex sounds such as speech. These nonlinearities set up contrast in the depth of neural-fluctuations in auditory-nerve responses along the tonotopic axis, referred to here as neural fluctuation contrast (NFC). Physiological support for the NFC coding hypothesis is reviewed, and predictions of several psychophysical phenomena, including masked detection and speech intelligibility, are presented. Lastly, a framework based on the NFC code for understanding how the medial olivocochlear (MOC) efferent system contributes to the coding of complex sounds is presented. By modulating cochlear gain control in response to both sound energy and fluctuations in neural responses, the MOC system is hypothesized to function not as a simple feedback gain-control device, but rather as a mechanism for enhancing NFC along the tonotopic axis, enabling robust encoding of complex sounds across a wide range of sound levels and in the presence of background noise. Effects of sensorineural hearing loss on the NFC code and on the MOC feedback system are presented and discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.