Evidence map›Paper›PMID 38310447›Full record

ArticleCurrent pharmaceutical biotechnology2024

Iron(III) Monoglycerolate as a New Biocompatible Precursor in the Synthesis of Bioactive Nanocomposite Glycerohydrogels.

Tat'yana Grigor'evna Khonina, Denis Sergeevich Tishin, Leonid Petrovich Larionov, Artur Vasil'evich Osipenko, Maria Nikolaevna Dobrinskaya, Ekaterina Anatol'evna Bogdanova, Maxim Sergeevich Karabanalov, Maria Alekseevna Bulatova, Elena Vladimirovna Shadrina, Oleg Nikolaevich Chupakhin

Abstract read
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Article in Current pharmaceutical biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Tat'yana Grigor'evna KhoninaPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia.ORCID 0000-0002-8746-7046
Denis Sergeevich TishinPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia.ORCID 0000-0003-1163-7229
Leonid Petrovich LarionovUral State Medical University, Yekaterinburg, Russia.ORCID 0000-0003-3878-9820
Artur Vasil'evich OsipenkoUral State Medical University, Yekaterinburg, Russia.
Maria Nikolaevna DobrinskayaUral State Medical University, Yekaterinburg, Russia.ORCID 0000-0001-9208-9417
Ekaterina Anatol'evna BogdanovaInstitute of Solid State Chemistry, Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia.ORCID 0000-0002-6947-5368
Maxim Sergeevich KarabanalovUral Federal University, Yekaterinburg, Russia.ORCID 0000-0001-6619-2816
Maria Alekseevna BulatovaPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia.ORCID 0009-0003-1945-4379
Elena Vladimirovna ShadrinaPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia.ORCID 0000-0002-2102-316X
Oleg Nikolaevich ChupakhinPostovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia.ORCID 0000-0002-1672-2476
Institute of Organic Synthesis · RUUral State Medical University · RUUral Federal University · RUInstitute of Solid State Chemistry · RU

Funding

Russian Science Foundation ?22-23-20032,22-23-20032,22-23-20032,project no. 22-23-20032Russian Science Support Foundation project no. 22-23-20032
6 · The paper itself

Abstract

backgroundNanocomposite glycerohydrogels based on biocompatible elementcontaining glycerolates are of practicular interest for biomedical applications.

objectiveUsing two biocompatible precursors, silicon and iron glycerolates, a new bioactive nanocomposite silicon‒iron glycerolates hydrogel was obtained by sol-gel method.

methodsThe composition and structural features of the hydrogel were studied using a complex of modern analytical techniques, including TEM, XRD, and AES. On the example of experimental animals hemostatic activity of the hydrogel was studied, as well as primary toxicological studies were carried out.

resultsThe composition of dispersed phase and dispersion medium of silicon‒iron glycerolates hydrogel was determined. The structural features of hydrogel were revealed and its structure model was proposed. It was shown that silcon-iron glycerolates hydrogel is nontoxic, and exhibits pronounced hemostatic activity.

conclusionSilicon-iron glycerolates hydrogel is a potential hemostatic agent for topical application in medical and veterinary practice.

Indexed as

Biocompatible MaterialsHydrogelsNanocompositesAnimalsFerric CompoundsGlycerolHemostaticsIronMaleSiliconBiocompatible MaterialsFerric CompoundsGlycerolHemostaticsHydrogelsIronSiliconbiocompatible precursorshemostatic activity.iron(III) monoglycerolatenanocomposite glycerohydrogelSilicon glycerolatessol-gel processing

Identifiers

PMID38310447
OpenAlexW4391522198

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.