Evidence map›Paper›PMID 38310403›Full record

ArticleArchives of Iranian medicine2023

Comparison of Disease Phenotype and Course among Elderly- and Early-Onset Inflammatory Bowel Diseases in the Middle East.

Hasan Vosoghinia, Bahar Saberzadeh-Ardestani, Amir Anushiravani, Fariborz Mansour-Ghanaei, Hafez Fakheri, Homayoon Vahedi, Farshad Sheikhesmaeili, Abbas Yazdanbod, Seyed Hamid Moosavy, Iradj Maleki and 15 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of Iranian medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 9 institutions in 2 countries.

Hasan VosoghiniaGastroenterology and Hepatology Department, Faculty of Medicine, Ghaem Hospital, Mashhad, Iran.ORCID 0000-0003-1635-2919
Bahar Saberzadeh-ArdestaniDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Amir AnushiravaniDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-9196-1901
Fariborz Mansour-GhanaeiGastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Hafez FakheriGut and Liver Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Homayoon VahediDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Farshad SheikhesmaeiliLiver and Digestive Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Abbas YazdanbodGastroenterology and Hepatology Department, Digestive Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Seyed Hamid MoosavyShahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Iradj MalekiGut and Liver Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Siavosh Nasseri-MoghaddamDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Bardia KhosraviDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Masoud MalekzadehDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Amir KasaeianDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Sudabeh AlatabDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Anahita SadeghiDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Shadi KolahdoozanDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad AmaniDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Seyedeh Naeimeh SaberhosseiniMashhad University of Medical Sciences, Mashhad, Iran.
Maryam RayatpishehDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mitra AhadiMashhad University of Medical Sciences, Mashhad, Iran.
Jean-Frederic ColombelThe Henry D. Janowitz Division of Gastroenterology Icahn School of Medicine at Mount Sinai, New York, USA.
Ryan C UngaroThe Henry D. Janowitz Division of Gastroenterology Icahn School of Medicine at Mount Sinai, New York, USA.
Ali Reza SimaDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Reza MalekzadehDigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRIcahn School of Medicine at Mount Sinai · USMashhad University of Medical Sciences · IRMazandaran University of Medical Sciences · IRArdabil University of Medical Sciences · IRGhaem Hospital · IRGuilan University of Medical Sciences · IRHormozgan University of Medical Sciences · IRKurdistan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is unknown if the clinical manifestations and phenotype of disease are comparable between early- and elderly-onset inflammatory bowel disease (IBD). We aimed to seek differences in disease phenotype, course, complications, and treatment between early- and elderly-onset IBD patients.

methodsThis retrospective cohort study on registered IBD patients in the Iranian Registry of Crohn's and Colitis (IRCC) compared demographics, disease phenotype, disease activity, IBD-related surgery and medications between early- and elderly-onset IBD. A generalized linear regression model was used to investigate the relative risk of age at diagnosis adjusted for gender and disease duration for the outcomes.

resultsFrom 10048 IBD patients, 749 with early-onset (7.5%), and 472 (4.7%) elderly-onset IBD were enrolled: 855 (63.1%) ulcerative colitis (UC) and 366 (26.9%) Crohn's disease (CD). Left-sided colitis was more frequent among elderly-onset UC patients (

conclusionEarly-onset IBD was associated with a more aggressive phenotype and higher prednisolone, immunomodulators, and anti-TNF use.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesAgedHumansImmunologic FactorsIranPhenotypePrednisoloneRetrospective StudiesTumor Necrosis Factor InhibitorsImmunologic FactorsPrednisoloneTumor Necrosis Factor InhibitorsCrohn’s diseaseEarly-onsetElderly-onsetInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID38310403
PMCPMC10862057
OpenAlexW4390232500

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.