Observational studyEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2024
Mortality after non-surgically treated acute type A aortic dissection is higher than previously reported.
Observational study in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Radiographic phenotyping of healthy and diseased aortas.Journal of cardiovascular imaging · 2026Article
- Readiness for Hospital Discharge and Quality of Life Among Patients Undergoing Surgery for Type A Aortic Dissection: A Prospective Observational Cohort Study.Nursing open · 2026Observational
- ADAR1 and ADAR2 Expression in the Thoracic Aortic Wall Correlates with Aneurysm Severity and Dissection Risk: Insights into A-to-I RNA Editing Dysregulation in Marfan Syndrome-Derived vSMCs.International journal of molecular sciences · 2026Article
- Cardiac POCUS in Undifferentiated Shock Revealing Aortic Dissection.Journal of clinical ultrasound : JCU · 2026Article
- Potential association of genetic variants with thoracic aortic aneurysm and dissection: Evidence from a Japanese community-based cohort.General thoracic and cardiovascular surgery · 2026Article
- Left main ostium dissection due to the ATAAD with coronary malperfusion.Journal of cardiothoracic surgery · 2026Article
- Type A Aortic Dissection: From Diagnosis to Cardiac Rehabilitation.Journal of clinical medicine · 2026Review
- Cold exposure increases aortic dissection risk through extracellular cold inducible RNA binding protein and toll like receptor 4 signaling.Scientific reports · 2026Article
- Endovascular repair of diseases originating in the ascending thoracic aorta: A systematic review and meta-analysis.JTCVS structural and endovascular · 2026Article
- Development and internal validation of a computed tomography angiography‑based prediction model for acute rupture in type A aortic dissection.Journal of thoracic disease · 2026Article
- Article
- Durable Left Ventricular Assist Device Implantation in a Patient With Iatrogenic Type A Aortic Dissection.JACC. Case reports · 2026Article
- Developing a carotid ultrasound radiomics-semantic fusion model to identify aortic dissection: a two-center retrospective study.Frontiers in medicine · 2026Article
- Deep learning in the early diagnosis of acute aortic dissection.Frontiers in cardiovascular medicine · 2026Review
- Rapid bedside multimodal ultrasound screening for acute type A aortic dissection: a perspective.Frontiers in cardiovascular medicine · 2026Article
- Aortic dissection as a disease of vascular wall homeostasis: integrating vasa vasorum-inflammation-metabolism axis for mechanistic insight and clinical translation.Frontiers in immunology · 2026Review
- Admission creatinine level predicts postoperative acute hepatic dysfunction in patients aged ≤30 years with acute type A aortic dissection: a multi-center retrospective study.Frontiers in cardiovascular medicine · 2026Article
- Construction and validation of explainable machine learning models to predict in-hospital mortality for patients with acute type A aortic dissection surgery.Frontiers in medicine · 2026Article
- Felt Versus Pericardium for the Sandwich Technique in Type A Aortic Dissection: A Human Cadaver Study.Journal of clinical medicine · 2025Article
- Prognostic factors and outcomes of acute type A aortic dissection: a retrospective clinical study.Journal of thoracic disease · 2025Article
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Abstract
objectivesIt has been commonly accepted that untreated acute type A aortic dissection (ATAAD) results in an hourly mortality rate of 1-2% during the 1st 24 h after symptom onset. The data to support this statement rely solely on patients who have been denied surgical treatment after reaching surgical centres. The objective was to perform a total review of non-surgically treated (NST) ATAAD and provide contemporary mortality data.
methodsThis was a regional, retrospective, observational study. All patients receiving one of the following diagnoses: International Classification of Diseases (ICD)-9 4410, 4411, 4415, 4416 or ICD-10 I710, I711, I715, I718 in an area of 1.9 million inhabitants in Southern Sweden during a period of 23 years (January 1998 to November 2021) were retrospectively screened. The search was conducted using all available medical registries so that every patient diagnosed with ATAAD in our region was identified. The charts and imaging of each screened patient were subsequently reviewed to confirm or discard the diagnosis of ATAAD.
resultsScreening identified 2325 patients, of whom 184 NST ATAAD patients were included. The mortality of NST ATAAD was 47.3 ± 4.4%, 55.0 ± 4.4%, 76.7 ± 3.7% and 83.9 ± 4.3% at 24 h, 48 h, 14 days and 1 year, respectively. The hourly mortality rate during the 1st 24 h after symptom onset was 2.6%.
conclusionsThis study observed higher mortality than has previously been reported. It emphasizes the need for timely diagnosis, swift management and emergent surgical treatment for patients suffering an acute type A aortic dissection.
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