ArticleEuropean geriatric medicine2024
Prognostic factors of poor outcomes in pneumonia in older adults: aspiration or frailty?
Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Factors driving outcome variability in aspiration and community-acquired pneumonia: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Development of an interprofessional education program for aspiration pneumonia care: an action research study.European geriatric medicine · 2026Article
- Trends in mortality in elderly patients with Alzheimer's dementia and aspiration pneumonitis in the United States.Neurodegenerative disease management · 2026Article
- Quantifying clinical indicators for identifying and prognosticating aspiration pneumonia in Chinese geriatric patients: a retrospective cohort study integrating multivariable regression and interpretable machine learning.Frontiers in medicine · 2026Article
- The hemoglobin-albumin-lymphocyte-platelet (HALP) score as a prognostic factor in patients with pneumonia aged 75 years and older.Journal of thoracic disease · 2025Article
- Predictive value of bedside lung ultrasound, quantitative chest CT, and frailty assessment for short-term outcomes in elderly patients with severe pneumonia: a pilot study.BMC pulmonary medicine · 2025Article
- Assessing the prevalence and the underdiagnosis of aspiration pneumonia among older hospitalized patients with community-acquired pneumonia using an artificial intelligence algorithm.Pneumonia (Nathan Qld.) · 2025Article
- Sarcopenia, dysphagia, and frailty in community-dwelling older adults: An analysis of mediation and moderated mediation models.Dysphagia · 2025Article
- Role of Antipseudomonal Antibiotics in Older Patients with Aspiration Pneumonia: A Nationwide Database Study in Japan.Antibiotics (Basel, Switzerland) · 2025Article
- Eating and Drinking with Acknowledged Risks (EDAR) in Older Adults: A Qualitative Study of the Experiences of Clinicians in Japan and the UK.Dysphagia · 2025Article
- Effect of pre-hospital living setting on nutritional intake route upon discharge in older adults with aspiration pneumonia: a prospective cohort study.BMC geriatrics · 2025Article
- Coagulation and inflammatory markers independently predict in-hospital mortality in aspiration pneumonia patients undergoing bronchoalveolar lavage.American journal of translational research · 2025Article
- Coagulation Parameters in Elderly Patients with Severe Pneumonia: Correlation with Disease Severity and Prognosis.Infection and drug resistance · 2025Article
- Article
- Pneumonia-Related Hospitalizations among the Elderly: A Retrospective Study in Northeast Italy.Diseases (Basel, Switzerland) · 2024Article
- The challenge of making better decisions about oral intake in older people with 'aspiration pneumonia'.European geriatric medicine · 2024Article
- Decisions on eating and drinking in older adults admitted with pneumonia and referred for swallowing difficulties.European geriatric medicine · 2024Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
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Abstract
purposeLittle is known about the long-term and functional prognoses of older adults with pneumonia, which complicates their management. There is a common belief that aspiration is a poor prognostic factor; however, the diagnosis of aspiration pneumonia (AP) lacks consensus criteria and is mainly based on clinical characteristics typical of the frailty syndrome. Therefore, the poor prognosis of AP may also be a result of frailty rather than aspiration. This study investigated the impact of AP and other prognostic factors in older patients with pneumonia.
methodsWe performed a retrospective cohort study of patients aged 75 years and older, admitted with pneumonia in 2021. We divided patients according to their initial diagnosis (AP or non-AP), compared outcomes using Kaplan-Meier curves, and used logistic regression to identify independent prognostic factors.
results803 patients were included, with a median age of 84 years and 52.7% were male. 17.3% were initially diagnosed with AP. Mortality was significantly higher in those diagnosed with AP than non-AP during admission (27.6% vs 19.0%, p = 0.024) and at 1 year (64.2% vs 53.1%, p = 0.018), with survival analysis showing a median survival time of 62 days and 274 days in AP and non-AP, respectively (χ
conclusionThe greater mortality in AP may be a result of increased frailty rather than the diagnosis of aspiration itself. This supports our proposal for a paradigm shift from making predictions based on the potentially futile labelling of AP or non-AP, to considering frailty and overall condition of the patient.
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