Evidence map›Paper›PMID 38309031›Full record

ArticleGynecologic oncology2024

Rural-urban disparities in psychosocial functioning in epithelial ovarian cancer patients.

Rachel Telles, M Bridget Zimmerman, Premal H Thaker, George M Slavich, Edgardo S Ramirez, Sharaf Zia, Michael J Goodheart, Steven W Cole, Anil K Sood, Susan K Lutgendorf

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gynecologic oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Rachel TellesDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
M Bridget ZimmermanDepartment of Preventive Medicine and Biostatistics, University of Iowa, Iowa City, IA, USA.
Premal H ThakerDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, Saint Louis, MO, USA.
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA.
Edgardo S RamirezDepartment of Psychology, University of California, Los Angeles, CA, USA.
Sharaf ZiaInstitute of Clinical and Translational Sciences, University of Iowa Hospital & Clinics, Iowa City, IA, USA.
Michael J GoodheartDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.
Steven W ColeDivision of Hematology-Oncology, University of California, Los Angeles School of Medicine, Los Angeles, CA, USA.
Anil K SoodDepartments of Gynecologic Oncology, Cancer Biology and Center for RNA Interference and Noncoding RNA, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Susan K LutgendorfDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA. Electronic address: susan-lutgendorf@uiowa.edu.
University of Iowa · USUniversity of California, Los Angeles · USNeurobehavioral Systems · USThe University of Texas MD Anderson Cancer Center · USUniversity of Iowa Hospitals and Clinics · USWashington University in St. Louis · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Jon C.D. Houtman · 2000 to 2026
$70.0M
Ovarian Cancer: Mechanisms of Neuroendocrine RegulationR01CA109298 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SOOD, ANIL K · 2005 to 2017
$4.5M
Behavioral Influences on Ovarian Cancer Progression: Role of ChemoresistanceR01CA193249 · NCI · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K · 2016 to 2020
$3.2M
Biobehavioral Influences and the Ovarian Tumor MicroenvironmentR01CA140933 · NCI · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K · 2009 to 2013
$2.8M
Mechanisms of Health and Disease at the Behavioral-Biomedical InterfaceT32GM108540 · NIGMS · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K, VOSS, MICHELLE WEBB · 2014 to 2023
$1.7M
NCI NIH HHS P30 CA086862NCI NIH HHS R01 CA109298NCI NIH HHS R01 CA140933NCI NIH HHS R01 CA193249NIGMS NIH HHS T32 GM108540
6 · The paper itself

Abstract

objectiveAlthough rural residence has been related to health disparities in cancer patients, little is known about how rural residence impacts mental health and quality of life (QOL) in ovarian cancer patients over time. This prospective longitudinal study investigated mental health and QOL of ovarian cancer patients in the first-year post-diagnosis.

methodWomen with suspected ovarian cancer completed psychosocial surveys pre-surgery, at 6 months and one-year; clinical data were obtained from medical records. Histologically confirmed high grade epithelial ovarian cancer patients were eligible. Rural/urban residence was categorized from patient counties using the USDA Rural-Urban Continuum Codes. Linear mixed effects models examined differences in psychosocial measures over time, adjusting for covariates.

resultsAlthough disparities were not observed at study entry for any psychosocial variable (all p-values >0.22), urban patients showed greater improvement in total distress over the year following diagnosis than rural patients (p = 0.025) and were significantly less distressed at one year (p = 0.03). Urban patients had a more consistent QOL improvement than their rural counterparts (p = 0.006). There were no differences in the course of depressive symptoms over the year (p = 0.17). Social support of urban patients at 12 months was significantly higher than that of rural patients (p = 0.04).

conclusionRural patients reported less improvement in psychological functioning in the year following diagnosis than their urban counterparts. Clinicians should be aware of rurality as a potential risk factor for ongoing distress. Future studies should examine causes of these health disparities and potential long-term inequities and develop interventions to address these issues.

Indexed as

Carcinoma, Ovarian EpithelialDepressionOvarian NeoplasmsPsychosocial FunctioningAdultAgedFemaleHealth Status DisparitiesHumansLongitudinal StudiesMental HealthMiddle AgedProspective StudiesPsychological DistressQuality of LifeResidence CharacteristicsDepressionOvarian cancer distressQuality of lifeRural urban health disparitiesSocial support

Identifiers

PMID38309031
PMCPMC11179980
OpenAlexW4391503403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.