ArticleThe journal of nutrition, health & aging2024
Association between abdominal adiposity and cognitive decline in older adults: a 10-year community-based study.
Article in The journal of nutrition, health & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 26 citations in OpenAlex.
- Effects of obesity on brain health and cognition.Nature reviews. Neurology · 2026Review
- Relationship Between Cognitive Performance and Anthropometric Status, Dietary Diversity, and Diet Quality in Older Turkish Adults: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Microbiota-Gut-Brain Axis Mechanisms in Cognitive Impairment Associated with Central Obesity.Current obesity reports · 2026Review
- Metabolic Syndrome and Dementia Risk in Older Adults: A Narrative Review.The Kaohsiung journal of medical sciences · 2026Review
- Article
- Neural Oscillatory and Network Signatures of Age-Related Cognitive Decline Under Motor-Cognitive Dual-Task Conditions.Brain sciences · 2026Article
- Nonlinear association between age and verbal fluency and moderation by adiposity: cross-sectional evidence from the Look Up 8+ study.Frontiers in aging neuroscience · 2026Article
- Intermittent fasting and immune aging: implications for immunosenescence, inflammaging, neuroinflammation, and frailty.Frontiers in nutrition · 2026Review
- Adipose tissue aging as a risk factor for metabolic organ abnormalities: mechanistic insights and the role of exercise interventions.Lipids in health and disease · 2025Review
- Does Energy Restriction and Loss of Body Fat Account for the Effect of Intermittent Fasting on Cognitive Function?Nutrients · 2025Review
- Body roundness index and mental health in middle-aged and elderly adults: a prospective cohort study.Scientific reports · 2025Article
- Obesity-associated memory impairment and neuroinflammation precede widespread peripheral perturbations in aged rats.Immunity & ageing : I & A · 2025Article
- Relationship between obesity indices and cognitive function in Japanese men: A cross-sectional study.PloS one · 2025Article
- Body composition and cognitive function in Chinese rural adults: an exploratory factor analysis and network analysis.Frontiers in aging neuroscience · 2025Article
- Relationship between Body Roundness Index and cognitive impairment in middle-aged and older adults: a population-based cross-sectional study.Frontiers in aging neuroscience · 2025Article
- Association between abdominal obesity and cognitive decline among Chinese middle-aged and older adults: a 10-year follow-up from CHARLS.Frontiers in public health · 2025Article
- Association between Obesity and Cognitive Function in Chinese Older Adults: The Mediating Effects of Sleep Quality and Blood Pressure.Current Alzheimer research · 2025Observational
- Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS.Frontiers in aging neuroscience · 2025Article
- Different factors modulate visceral and subcutaneous fat accumulation in adults: a single-center study in Brazil.Frontiers in nutrition · 2025Article
- Association of different obesity indexes with diabetic kidney disease in patients with type 2 diabetes mellitus: a cross-sectional study.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to investigate the association between abdominal adiposity and change in cognitive function in community-dwelling older adults. DESIGN, SETTING, AND
participantsThis longitudinal study included older adults aged ≥60 years without cognitive impairment who participated in the National Institute for Longevity Sciences - Longitudinal Study of Aging. MEASUREMENTS: Cognitive function was evaluated biennially using the Mini-Mental State Examination (MMSE) over 10 years. Waist circumference (WC) was measured at the naval level, and subcutaneous fat area (SFA) and visceral fat area (VFA) were assessed using baseline computed tomography scans. WC, SFA, and VFA areas were stratified into sex-adjusted tertiles. A linear mixed model was applied separately for men and women.
resultsThis study included 873 older adults. In men, the groups with the highest levels of WC, SFA, and VFA exhibited a greater decline in MMSE score than the groups with the lowest levels (β [95% confidence interval]: WC, -0.12 [-0.23 to -0.01]; SFA, -0.13 [-0.24 to -0.02]; VFA, -0.11 [-0.22 to -0.01]). In women, the group with the highest level of WC and SFA showed a greater decline in MMSE score than the group with the lowest level (WC, -0.12 [-0.25 to -0.01]; SFA, -0.18 [-0.30 to -0.06]), but VFA was not associated with cognitive decline.
conclusionHigher WC, SFA, and VFA in men and higher WC and SFA in women were identified as risk factors for cognitive decline in later life, suggesting that abdominal adiposity involved in cognitive decline may differ according to sex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.