Evidence map›Paper›PMID 38308650›Full record

ArticleThe Journal of organic chemistry2024

Regio- and Enantioselective Asymmetric Transfer Hydrogenation of One Carbonyl Group in a Diketone through Steric Hindrance.

Noha Khamis, Ye Zheng, Marianna N Diamantakis, Guy J Clarkson, Jie Liu, Martin Wills

Open access · hybridAbstract read
In one paragraph

Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Noha KhamisDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.
Ye ZhengDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.
Marianna N DiamantakisDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.
Guy J ClarksonDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0003-3076-3191
Jie LiuDepartment of Physics, The University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0002-1301-057X
Martin WillsDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0002-1646-2379
University of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On the basis of steric hindrance, one carbonyl group in a diketone can be reduced in a regioselective manner, with high enantioselectivity. The methodology can be extended to ketones with varied length of hydrocarbon chain spacing, and the products can be converted by oxidation to hydroxy esters or lactones without loss of enantiopurity.

Identifiers

PMID38308650
PMCPMC10877611
OpenAlexW4391509232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.