Evidence map›Paper›PMID 38308532›Full record

ArticleBiochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

An interdisciplinary course on computer-aided drug discovery to broaden student participation in original scientific research.

Christopher Stratton, Avery Christensen, Chelsey Jordan, Brian A Salvatore, Elahe Mahdavian

Abstract read
In one paragraph

Article in Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Biochemistry Learning in Higher Education: A Systematic Review on Methodologies and Teaching Resources.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher StrattonDepartment of Biological Science, LSU Shreveport, One University Place, Shreveport, Louisiana, USA.
Avery ChristensenDepartment of Biological Science, LSU Shreveport, One University Place, Shreveport, Louisiana, USA.
Chelsey JordanDepartment of Biological Science, LSU Shreveport, One University Place, Shreveport, Louisiana, USA.
Brian A SalvatoreDepartment of Chemistry & Physics, LSU Shreveport, One University Place, Shreveport, Louisiana, USA.
Elahe MahdavianDepartment of Biological Science, LSU Shreveport, One University Place, Shreveport, Louisiana, USA.ORCID 0000-0003-1117-9117

Funding

STABILITY' (symptomatic review during biologic therapy) Review in Inflammatory Bowel DiseaseP20GM103424 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI Seetharama D Jois · 2012 to 2026
$57.4M
Louisiana Biomedical Research Network P20GM103424-21NIGMS NIH HHS P20 GM103424
6 · The paper itself

Abstract

We present a new highly interdisciplinary project-based course in computer aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational experiences for chemistry, biology, and computer science students. We implement research-based methods with publicly available tools in bioinformatics and molecular modeling to identify and prioritize promising antiviral drug candidates for COVID-19. The purpose of this course is three-fold: I. Implement an active learning and inclusive pedagogy that fosters student engagement and research mindset; II. Develop student interdisciplinary research skills that are highly beneficial in a broader scientific context; III. Demonstrate that pedagogical shifts (initially incurred during the COVID-19 pandemic) can furnish longer-term instructional benefits. The course, which has now been successfully taught a total of five times, incorporates four modules, including lectures/discussions, live demos, inquiry-based assignments, and science communication.

Indexed as

COVID-19Drug DiscoverySARS-CoV-2StudentsAntiviral AgentsBiomedical ResearchComputational BiologyCurriculumHumansPandemicsProblem-Based LearningAntiviral AgentsbioinformaticsCADDCOVID‐19CUREguided researchinclusive pedagogyinterdisciplinarySwissADMESwissBioisostereSwissSimilarity

Identifiers

PMID38308532
PMCPMC11251704

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.