Evidence map›Paper›PMID 38308479›Full record

ArticleTissue engineering. Part A2024

Metformin Treatment of Macrophages Increases Microvessel Growth in Three-Dimensional Hydrogel Coculture.

Justin Silberman, Michael Olagbiyan, Erika Moore

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part A, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Justin SilbermanDepartment of Materials Science and Engineering, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-5749-7471
Michael OlagbiyanJ. Crayton Pruitt Department of Biomedical Engineering, University of Florida, Gainesville, Florida, USA.
Erika MooreDepartment of Materials Science and Engineering, University of Florida, Gainesville, Florida, USA.ORCID 0000-0003-2192-6147
University of Florida · US

Funding

Training Program in Regenerative MedicineT32DK074367 · NIDDK · UNIVERSITY OF FLORIDA · PI SCOTT, EDWARD W · 2007 to 2022
$2.9M
NIDDK NIH HHS T32 DK074367
6 · The paper itself

Abstract

The global population is aging rapidly, posing unprecedented challenges to health care systems. This study investigates the often-overlooked role of macrophages in microvascular dysfunction associated with aging. We use a three-dimensional

Indexed as

Coculture TechniquesHydrogelsMacrophagesMetforminMicrovesselsChemokine CCL2HumansHuman Umbilical Vein Endothelial CellsNeovascularization, PhysiologicChemokine CCL2HydrogelsMetforminagingbiomaterialmacrophagemetforminvasculogenesis

Identifiers

PMID38308479
PMCPMC11573715
OpenAlexW4391512226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.