Evidence map›Paper›PMID 38308337›Full record

ArticleBMC rheumatology2024

Risk of venous thromboembolism in patients with rheumatoid arthritis: a meta-analysis of observational studies.

Zahra A Fazal, Ana Michelle Avina-Galindo, Shelby Marozoff, Jessie Kwan, Na Lu, J Antonio Avina-Zubieta

Open access · goldAbstract read
In one paragraph

Article in BMC rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. The risk of venous thromboembolism in RA.Rheumatology (Oxford, England) · 2026
    Review
  5. Article
  6. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zahra A Fazal *Arthritis Research Canada, 230-2238 Yukon Street, BC, V5Y 3P2, Vancouver, Canada.
Ana Michelle Avina-Galindo *Arthritis Research Canada, 230-2238 Yukon Street, BC, V5Y 3P2, Vancouver, Canada.
Shelby MarozoffArthritis Research Canada, 230-2238 Yukon Street, BC, V5Y 3P2, Vancouver, Canada.
Jessie KwanArthritis Research Canada, 230-2238 Yukon Street, BC, V5Y 3P2, Vancouver, Canada.
Na LuArthritis Research Canada, 230-2238 Yukon Street, BC, V5Y 3P2, Vancouver, Canada.
J Antonio Avina-ZubietaArthritis Research Canada, 230-2238 Yukon Street, BC, V5Y 3P2, Vancouver, Canada. azubieta@arthritisresearch.ca.
Arthritis Research Centre of Canada · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thrombosis (DVT) and pulmonary embolism (PE), in adults with RA compared to the general population.

methodsMEDLINE and EMBASE databases were searched from inception to April 2022 to identify publications meeting the following criteria: (1) prospective and retrospective original data from cohort or case-control studies; (2) pre-specified RA definition; (3) clearly defined VTE outcomes; (4) reported risk estimate and 95% confidence intervals (95% CIs); (5) at least sex- and age-matched to comparison group; and (6) English language. Of 372 studies screened, 14 were included (602,760 RA patients, 123,076 VTE events) and their quality was assessed by an adaptation of the STROBE quality scoring scale.

resultsThe pooled risk ratios of VTE, DVT and PE in patients with RA were 1.57 (95% CI 1.41-1.76), 1.58 (95% CI 1.26-1.97) and 1.57 (95% CI 1.30-1.88), respectively. The I

conclusionsResults show that patients with RA are at a higher risk of VTE, DVT and PE compared to the general population.

Indexed as

Deep vein thrombosisRheumatoid arthritisRiskThrombosisVenous thromboembolism

Identifiers

PMID38308337
PMCPMC10836002
OpenAlexW4391485351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.