Evidence map›Paper›PMID 38308149›Full record

ArticleMagnetic resonance in medicine2024

Self-supervised multicontrast super-resolution for diffusion-weighted prostate MRI.

Batuhan Gundogdu, Milica Medved, Aritrick Chatterjee, Roger Engelmann, Avery Rosado, Grace Lee, Nisa C Oren, Aytekin Oto, Gregory S Karczmar

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Combined ADC and TMagnetic resonance in medicine · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Batuhan GundogduDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-9395-7519
Milica MedvedDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-2945-5511
Aritrick ChatterjeeDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-4022-7106
Roger EngelmannDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.
Avery RosadoDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.
Grace LeeDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.
Nisa C OrenDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.
Aytekin OtoDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.
Gregory S KarczmarDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-2455-5858

Funding

Detection of prostate Cancer Specific Signals with Hybrid Multi-Dimensional MRIR01CA228036 · NCI · UNIVERSITY OF CHICAGO · PI KARCZMAR, GREGORY S., OTO, AYTEKIN · 2019 to 2023
$2.7M
3T MRI Scanner for multidisciplinary imaging and image-guided therapyS10OD018448 · OD · UNIVERSITY OF CHICAGO · PI KARCZMAR, GREGORY S. · 2014 to 2014
$2.0M
MR Virtual Pathology of the ProstateR41CA244056 · NCI · QMIS, LLC · PI KARCZMAR, GREGORY S., MUSTAFI, DEVKUMAR · 2020 to 2020
$225k
Foundation for the National Institutes of Health 1R41CA244056-01A1Foundation for the National Institutes of Health 1S10OD018448-01Foundation for the National Institutes of Health R01 CA17280Foundation for the National Institutes of Health R01 CA227036NCI NIH HHS R01 CA228036NCI NIH HHS R41 CA244056NIH HHS S10 OD018448Sanford J. Grossman Charitable TrustUniversity of Chicago Medicine Comprehensive Cancer Center P30 CA014599-37
6 · The paper itself

Abstract

purposeThis study addresses the challenge of low resolution and signal-to-noise ratio (SNR) in diffusion-weighted images (DWI), which are pivotal for cancer detection. Traditional methods increase SNR at high b-values through multiple acquisitions, but this results in diminished image resolution due to motion-induced variations. Our research aims to enhance spatial resolution by exploiting the global structure within multicontrast DWI scans and millimetric motion between acquisitions.

methodsWe introduce a novel approach employing a "Perturbation Network" to learn subvoxel-size motions between scans, trained jointly with an implicit neural representation (INR) network. INR encodes the DWI as a continuous volumetric function, treating voxel intensities of low-resolution acquisitions as discrete samples. By evaluating this function with a finer grid, our model predicts higher-resolution signal intensities for intermediate voxel locations. The Perturbation Network's motion-correction efficacy was validated through experiments on biological phantoms and in vivo prostate scans.

resultsQuantitative analyses revealed significantly higher structural similarity measures of super-resolution images to ground truth high-resolution images compared to high-order interpolation (p

conclusionHigh-resolution details in DWI can be obtained without the need for high-resolution training data. One notable advantage of the proposed method is that it does not require a super-resolution training set. This is important in clinical practice because the proposed method can easily be adapted to images with different scanner settings or body parts, whereas the supervised methods do not offer such an option.

Indexed as

AlgorithmsDiffusion Magnetic Resonance ImagingPhantoms, ImagingProstateProstatic NeoplasmsSignal-To-Noise RatioHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMaleMotionNeural Networks, ComputerReproducibility of ResultsDWIimplicit neural representationprostate MRIsuper‐resolution for MRI

Identifiers

PMID38308149
PMCPMC11288973

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.