Evidence map›Paper›PMID 38308119›Full record

ArticleLasers in medical science2024

Ablative fractional laser treatment reduces hedgehog pathway gene expression in murine basal cell carcinomas.

Kristian Kåber Pedersen, Jonatan Riber Granborg, Catharina Margrethe Lerche, Thomas Litman, Uffe Høgh Olesen, Merete Hædersdal

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kristian Kåber PedersenDepartment of Dermatology, Copenhagen University Hospital Bispebjerg, 2400, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-9994-7848
Jonatan Riber GranborgDepartment of Dermatology, Copenhagen University Hospital Bispebjerg, 2400, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-5887-630X
Catharina Margrethe LercheDepartment of Dermatology, Copenhagen University Hospital Bispebjerg, 2400, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-3653-6424
Thomas LitmanDepartment of Immunology and Microbiology, University of Copenhagen, 2200, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-6068-901X
Uffe Høgh OlesenDepartment of Dermatology, Copenhagen University Hospital Bispebjerg, 2400, Copenhagen, Denmark. uffe.hoegh.olesen@regionh.dk.ORCID http://orcid.org/0000-0002-4578-684X
Merete HædersdalDepartment of Dermatology, Copenhagen University Hospital Bispebjerg, 2400, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-1250-2035
Bispebjerg Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the impact of ablative fractional laser (AFL) on hedgehog pathway gene expression in murine microscopic basal cell carcinomas (BCCs) and compare these results to the effect of topical treatment with vismodegib, an FDA-approved hedgehog inhibitor. In 25 mice, 1 cm

Indexed as

AnilidesBasal Cell CarcinomaPyridinesSkin NeoplasmsAnimalsGene ExpressionHedgehog ProteinsLasersMiceZinc Finger Protein GLI1AnilidesHedgehog ProteinsHhAntag691PyridinesZinc Finger Protein GLI1Ablative fractional laserBasal cell carcinomaHedgehog inhibitorsMurine tumor modelVismodegib

Identifiers

PMID38308119
PMCPMC10837214
OpenAlexW4391513638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.