Evidence map›Paper›PMID 38308019›Full record

ArticleAnnals of hematology2024

A nomogram model for predicting the efficacy of cyclosporine in patients with pure red cell aplasia.

Liyan Yang, Haiyue Niu, Tian Zhang, Qiuying Cao, Mengyuan Liu, Yumei Liu, Li Yan, Weiwei Qi, Ting Wang, Chunyan Liu and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Molecular landscape of CD8Annals of hematology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Liyan YangDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Haiyue NiuDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Tian ZhangDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Qiuying CaoDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Mengyuan LiuDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Yumei LiuDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Li YanDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Weiwei QiDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Ting WangDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Chunyan LiuDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Lijuan LiDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Limin XingDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China.
Huaquan WangDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China. wanghuaquan@tmu.edu.cn.ORCID http://orcid.org/0000-0003-2402-2717
Zonghong ShaoDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China. shaozonghong@sina.com.
Rong FuDepartment of Hematology, General Hospital, Tianjin Medical University, No. 154 Anshandao Road, Heping District, Tianjin, 300052, China. florai@sina.com.
Tianjin Medical University General Hospital · CN

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 81170472Innovative Research Group Project of the National Natural Science Foundation of China 81970115Innovative Research Group Project of the National Natural Science Foundation of China 82270139Key Technologies Research and Development Program 18ZXDBSY00140The Zhaoyicheng Medical Science Foundation of Tianjin China ZYYFY2018026Tianjin Municipal Science and Technology Committee TJWJ2023QN006Tianjin Research Program of Application Foundation and Advanced Technology of China 09JCYBJC11200Tianjin Research Program of Application Foundation and Advanced Technology of China 14JCYBJC27200
6 · The paper itself

Abstract

Pure red cell aplasia (PRCA) is a rare bone marrow disorder characterized by a severe reduction or absence of erythroid precursor cells, without affecting granulocytes and megakaryocytes. Immunosuppressive therapies, particularly cyclosporine, have demonstrated efficacy as a primary treatment. This study aims to develop a predictive model for assessing the efficacy of cyclosporine in acquired PRCA (aPRCA). This retrospective study encompasses newly treated aPRCA patients at the General Hospital of Tianjin Medical University. Diagnosis criteria include severe anemia, and absolute reticulocyte count below 10 × 10

Indexed as

CyclosporineNomogramsRed-Cell Aplasia, PureAdultAgedAged, 80 and overFemaleHumansImmunosuppressive AgentsMaleMiddle AgedRetrospective StudiesTreatment OutcomeCyclosporineImmunosuppressive AgentsAcquired pure red cell aplasiaCyclosporineFerritinLymphocytePredictive models

Identifiers

PMID38308019
OpenAlexW4391513640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.