Evidence map›Paper›PMID 38307877›Full record

ArticleNature communications2024

Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma.

Ling-Hui Zeng, Chao Tang, Minli Yao, Qiangqiang He, Meiyu Qv, Qianlei Ren, Yana Xu, Tingyu Shen, Weizhong Gu, Chengyun Xu and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Ling-Hui Zeng *Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang, Province, Hangzhou City University School of Medicine, Hangzhou, 310015, China. zenglh@zucc.edu.cn.ORCID 0000-0002-3758-0366
Chao Tang *Department of Pharmacology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Minli Yao *Department of Pharmacology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Qiangqiang HeDepartment of Pharmacology, Zhejiang University School of Medicine, Hangzhou, 310058, China.ORCID 0009-0004-5753-9362
Meiyu QvKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang, Province, Hangzhou City University School of Medicine, Hangzhou, 310015, China.ORCID 0000-0001-7736-6375
Qianlei RenKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang, Province, Hangzhou City University School of Medicine, Hangzhou, 310015, China.
Yana XuDepartment of Pharmacology, Zhejiang University School of Medicine, Hangzhou, 310058, China.ORCID 0009-0006-1474-0677
Tingyu ShenDepartment of Pharmacology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Weizhong GuNational Clinical Research Center for Child Health, the Children's Hospital of Zhejiang University School of Medicine, Hangzhou, 310053, China.
Chengyun XuKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang, Province, Hangzhou City University School of Medicine, Hangzhou, 310015, China.
Chaochun ZouNational Clinical Research Center for Child Health, the Children's Hospital of Zhejiang University School of Medicine, Hangzhou, 310053, China.
Xing JiKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang, Province, Hangzhou City University School of Medicine, Hangzhou, 310015, China.
Ximei WuDepartment of Pharmacology, Zhejiang University School of Medicine, Hangzhou, 310058, China. xiwu@zju.edu.cn.ORCID 0000-0002-3316-893X
Jirong WangDepartment of Geriatrics, Zhejiang Provincial Key Lab of Geriatrics, Zhejiang Hospital, Hangzhou, 310030, China. wangjr@zju.edu.cn.ORCID 0000-0001-6172-852X
Sir Run Run Shaw Hospital · CNChildren's Hospital of Zhejiang University · CNHangzhou City UniversityZhejiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant activation of sonic hedgehog (SHH) signaling and its effector transcriptional factor GLI1 are essential for oncogenesis of SHH-dependent medulloblastoma (MB

Indexed as

Cerebellar NeoplasmsMedulloblastomaAnimalsChildHedgehog ProteinsHumansMiceOncogenesPhosphorylationZinc Finger Protein GLI1GLI1 protein, humanHedgehog ProteinsSHH protein, humanZinc Finger Protein GLI1

Identifiers

PMID38307877
PMCPMC10837140
OpenAlexW4391474145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.