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ArticleMolecular biology and evolution2024

The Dynamic Interplay Between Ribosomal DNA and Transposable Elements: A Perspective From Genomics and Cytogenetics.

Sònia Garcia, Ales Kovarik, Sophie Maiwald, Ludwig Mann, Nicola Schmidt, Joan Pere Pascual-Díaz, Daniel Vitales, Beatrice Weber, Tony Heitkam

Abstract read
In one paragraph

Article in Molecular biology and evolution, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Dynamic evolution and hierarchical regulation of rDNA in polyploid oat.The Plant journal : for cell and molecular biology · 2026
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  2. Article
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  9. Repeatome Analysis and Satellite DNA Chromosome Patterns inInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sònia GarciaInstitut Botànic de Barcelona (IBB), CSIC-CMCNB, 08038 Barcelona, Catalonia, Spain.ORCID 0000-0002-3143-0527
Ales KovarikInstitute of Biophysics, Academy of Sciences of the Czech Republic, 61265 Brno, Czech Republic.ORCID 0000-0003-2896-0698
Sophie MaiwaldFaculty of Biology, Technische Universität Dresden, D-01069 Dresden, Germany.ORCID 0000-0002-0716-648X
Ludwig MannFaculty of Biology, Technische Universität Dresden, D-01069 Dresden, Germany.ORCID 0000-0001-8756-8106
Nicola SchmidtFaculty of Biology, Technische Universität Dresden, D-01069 Dresden, Germany.ORCID 0000-0003-0038-9581
Joan Pere Pascual-DíazInstitut Botànic de Barcelona (IBB), CSIC-CMCNB, 08038 Barcelona, Catalonia, Spain.ORCID 0000-0002-5984-6815
Daniel VitalesInstitut Botànic de Barcelona (IBB), CSIC-CMCNB, 08038 Barcelona, Catalonia, Spain.ORCID 0000-0002-3109-5028
Beatrice WeberFaculty of Biology, Technische Universität Dresden, D-01069 Dresden, Germany.ORCID 0000-0003-4012-4430
Tony HeitkamFaculty of Biology, Technische Universität Dresden, D-01069 Dresden, Germany.ORCID 0000-0003-0168-8428

Funding

Agencia Estatal de Investigación PID2020-119163GB-I00Bundesministerium für Bildung und ForschungCzech Science Foundation 22-16826SGerman Research FoundationGraduate Academy of the TU Dresden
6 · The paper itself

Abstract

Although both are salient features of genomes, at first glance ribosomal DNAs and transposable elements are genetic elements with not much in common: whereas ribosomal DNAs are mainly viewed as housekeeping genes that uphold all prime genome functions, transposable elements are generally portrayed as selfish and disruptive. These opposing characteristics are also mirrored in other attributes: organization in tandem (ribosomal DNAs) versus organization in a dispersed manner (transposable elements); evolution in a concerted manner (ribosomal DNAs) versus evolution by diversification (transposable elements); and activity that prolongs genomic stability (ribosomal DNAs) versus activity that shortens it (transposable elements). Re-visiting relevant instances in which ribosomal DNA-transposable element interactions have been reported, we note that both repeat types share at least four structural and functional hallmarks: (1) they are repetitive DNAs that shape genomes in evolutionary timescales, (2) they exchange structural motifs and can enter co-evolution processes, (3) they are tightly controlled genomic stress sensors playing key roles in senescence/aging, and (4) they share common epigenetic marks such as DNA methylation and histone modification. Here, we give an overview of the structural, functional, and evolutionary characteristics of both ribosomal DNAs and transposable elements, discuss their roles and interactions, and highlight trends and future directions as we move forward in understanding ribosomal DNA-transposable element associations.

Indexed as

DNA Transposable ElementsGenomicsCytogenetic AnalysisDNA MethylationDNA, RibosomalEvolution, MolecularDNA, RibosomalDNA Transposable Elementsconcerted evolutiongenome sizegenome stabilityhomogenizationhousekeeping geneslong-read sequencingmolecular cytogeneticsrecombinationrepetitive DNAribosomal DNAtransposable elementstransposition

Identifiers

PMID38306580
PMCPMC10946416

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.