ArticleThe international journal of cardiovascular imaging2024
Myocardial work across different etiologies of right ventricular dysfunction and healthy controls.
Article in The international journal of cardiovascular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Integrated Mindfulness and Cardiopulmonary Rehabilitation Improves Cardiopulmonary Performance and Psychological Stress in Pulmonary Arterial Hypertension.Canadian respiratory journal · 2026Trial
- Right Ventricular Myocardial Work by Echocardiography: A Scoping Review of Methodology, Validation, and Clinical Applications.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Noninvasive biventricular pressure-strain-volume loop-derived myocardial work analysis in competitive athletes.Scientific reports · 2026Article
- Analysis of the effectiveness of the myocardial work index in the assessment of cancer therapy-related cardiac dysfunction.American journal of translational research · 2026Article
- Right ventricular global constructive work as an echocardiographic predictor of worsening heart failure.European heart journal open · 2026Article
- Prognostic Value of Right Ventricular Global Wasted Work in Precapillary Pulmonary Hypertension: A 3D Echocardiographic Study.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- Right ventricular global work efficiency: A reliable non-invasive estimate of right ventricular contractility.ESC heart failure · 2025Article
- Accuracy and reliability of non-invasive pressure-strain loop for myocardial work assessment in functional single ventricle patients.BMC cardiovascular disorders · 2025Article
- Echocardiographic Imaging to Guide Tricuspid Interventions.Structural heart : the journal of the Heart Team · 2025Review
- Shedding Light on the Dark Side of the Moon-Understanding Pediatric Right Ventricular Work in Pulmonary Hypertension.Pulmonary circulation · 2025Article
- Right ventricular myocardial work: proof-of-concept for the assessment of pressure-strain loops of patients with pre-capillary pulmonary hypertension.Cardiovascular ultrasound · 2025Article
- Asymmetric right ventricular myocardial work correlates with gold standard measurements of cardiac function in pulmonary hypertension.Pulmonary circulation · 2024Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evaluating right ventricular (RV) function remains a challenge. Recently, novel echocardiographic assessment of RV myocardial work (RVMW) by non-invasive pressure-strain loops was proposed. This enables evaluation of right ventriculoarterial coupling and quantifies RV dyssynchrony and post-systolic shortening. We aimed to assess RVMW in patients with different etiologies of RV dysfunction and healthy controls. We investigated healthy controls (n=17), patients with severe functional tricuspid regurgitation (FTR; n=22), and patients with precapillary pulmonary hypertension (PCPH; n=20). Echocardiography and right heart catheterization were performed to assess 1) RV global constructive work (RVGCW; work needed for systolic myocardial shortening and isovolumic relaxation), 2) RV global wasted work (RVGWW; myocardial shortening following pulmonic valve closure), and 3) RV global work efficiency (RVGWE; describes the relation between RV constructive and wasted work). RVGCW correlated with invasive RV stroke work index (r=0.66, P<0.001) and increased in tandem with higher afterload, i.e., was low in healthy controls (454±73 mmHg%), moderate in patients with FTR (687±203 mmHg%), and highest among patients with PCPH (881±255 mmHg%). RVGWE was lower and RVGWW was higher in patients with FTR (86±8% and 91 mmHg% [53-140]) or PCPH (86±10% and 110 mmHg% [66-159]) as compared with healthy controls (96±3% and 10 mmHg%). RVMW by echocardiography provides a promising index of RV function to discriminate between patients with RV volume or pressure overload. The prognostic value of this measure needs to be settled in future studies.
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