Evidence map›Paper›PMID 38305926›Full record

ArticleJournal of cancer research and clinical oncology2024

A subregion-based RadioFusionOmics model discriminates between grade 4 astrocytoma and glioblastoma on multisequence MRI.

Ruili Wei, Songlin Lu, Shengsheng Lai, Fangrong Liang, Wanli Zhang, Xinqing Jiang, Xin Zhen, Ruimeng Yang

Abstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  7. MRI-based habitat imaging predicts high-risk molecular subtypes and early risk assessment of lower-grade gliomas.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruili Wei *Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, GuangZhou, China.
Songlin Lu *School of Biomedical Engineering, Southern Medical University, GuangZhou, China.
Shengsheng LaiSchool of Medical Equipment, Guangdong Food and Drug Vocational College, Guangzhou, China.
Fangrong LiangDepartment of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, GuangZhou, China.
Wanli ZhangDepartment of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, GuangZhou, China.
Xinqing JiangDepartment of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, GuangZhou, China.
Xin ZhenSchool of Biomedical Engineering, Southern Medical University, GuangZhou, China. xinzhen@smu.edu.cn.
Ruimeng YangDepartment of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, GuangZhou, China. eyruimengyang@scut.edu.cn.

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2021A1515220060Guangzhou Key Laboratory of Molecular Imaging and Clinical Translational Medicine 202201020376National Natural Science Foundation of China 81874216National Natural Science Foundation of China 81971574Natural Science Foundation of Guangdong Province 2021A1515011350Natural Science Foundation of Guangdong Province 2022A1515011410Science and Technology Project of Guangzhou 202102010025
6 · The paper itself

Abstract

purposeTo explore a subregion-based RadioFusionOmics (RFO) model for discrimination between adult-type grade 4 astrocytoma and glioblastoma according to the 2021 WHO CNS5 classification.

methods329 patients (40 grade 4 astrocytomas and 289 glioblastomas) with histologic diagnosis was retrospectively collected from our local institution and The Cancer Imaging Archive (TCIA). The volumes of interests (VOIs) were obtained from four multiparametric MRI sequences (T

resultsThe two best VOIs were manual VOI

conclusionThe performance of subregions defined by clustering was comparable to that of subregions that were manually defined. Fusion of features from the edematous subregions of multiple MRI sequences by the RFO model resulted in differentiation between grade 4 astrocytoma and glioblastoma.

Indexed as

Brain NeoplasmsGlioblastomaAdultEdemaHumansMagnetic Resonance ImagingRetrospective StudiesAlgorithmAstrocytomaGlioblastomaMagnetic Resonance ImagingRadiomics

Identifiers

PMID38305926
PMCPMC10837235

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.