Evidence map›Paper›PMID 38305846›Full record

ReviewCurrent hypertension reports2024

Strategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review.

James P Sheppard, Athanase Benetos, Jonathan Bogaerts, Danijela Gnjidic, Richard J McManus

Open access · hybridAbstract readReview
In one paragraph

Review in Current hypertension reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

James P SheppardNuffield Department of Primary Care Health Sciences, Radcliffe Primary Care Building, Radcliffe Observatory Quarter, University of Oxford, Oxford, OX2 6GG, UK. james.sheppard@phc.ox.ac.uk.
Athanase BenetosCHRU-Nancy, Pôle "Maladies du Vieillissement, Gérontologie Et Soins Palliatifs", and Inserm DCAC u1116, Université de Lorraine, 54000, Nancy, France.
Jonathan BogaertsDepartment of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
Danijela GnjidicSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, 2006, Australia.
Richard J McManusNuffield Department of Primary Care Health Sciences, Radcliffe Primary Care Building, Radcliffe Observatory Quarter, University of Oxford, Oxford, OX2 6GG, UK.
Inserm · FRJohn Radcliffe Hospital · GBLeiden University Medical Center · NLThe University of Sydney · AUUniversity of Oxford · GB

Funding

Agence Nationale de Recherche ANR-15-RHU-0004British Heart Foundation PG/21/10341National French program of Hospital Clinical Research AOM16549/PHRC-16-0549Wellcome Trust 211182/Z/18/ZWellcome Trust/Royal Society 211182/Z/18/Z
6 · The paper itself

Abstract

purpose of reviewTo summarise the evidence regarding which patients might benefit from deprescribing antihypertensive medications. RECENT

findingsOlder patients with frailty, multi-morbidity and subsequent polypharmacy are at higher risk of adverse events from antihypertensive treatment, and therefore may benefit from antihypertensive deprescribing. It is possible to examine an individual's risk of these adverse events, and use this to identify those people where the benefits of treatment may be outweighed by the harms. While such patients might be considered for deprescribing, the long-term effects of this treatment strategy remain unclear. Evidence now exists to support identification of those who are at risk of adverse events from antihypertensive treatment. These patients could be targeted for deprescribing interventions, although the long-term benefits and harms of this approach are unclear. PERSPECTIVES: Randomised controlled trials are still needed to examine the long-term effects of deprescribing in high-risk patients with frailty and multi-morbidity.

Indexed as

Antihypertensive AgentsDeprescriptionsHypertensionBlood PressureFrailtyHumansPolypharmacyAntihypertensive AgentsAgingDrug-related side effects and adverse reactionsFrailtyHypertensionMulti-morbidityPolypharmacyRisk prediction

Identifiers

PMID38305846
PMCPMC11153298
OpenAlexW4391484577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.