Evidence map›Paper›PMID 38305176›Full record

ArticlemSphere2024

Short-chain fatty acids of various lengths differentially inhibit

Kai Chirng Chang, Niranjan Nagarajan, Yunn-Hwen Gan

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 25 citations in OpenAlex.

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  6. The Role of Gut Microbiota in Acute Myeloid Leukemia.Journal of clinical medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kai Chirng ChangYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0009-0005-1862-9557
Niranjan NagarajanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yunn-Hwen GanDepartment of Biochemistry, Infectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0001-9881-6881
National University of Singapore · SGAgency for Science, Technology and Research · SG

Funding

MOH | National Medical Research Council (NMRC) OFLCG22may-0009National University of Singapore (NUS) Reimagine Type I Fund (A-0002500-00-00)
6 · The paper itself

Abstract

The gut microbiota is inextricably linked to human health and disease. It can confer colonization resistance against invading pathogens either through niche occupation and nutrient competition or via its secreted metabolites. Short-chain fatty acids (SCFA) are the primary metabolites in the gut as a result of dietary fiber fermentation by the gut microbiota. In this work, we demonstrate that the interaction of single-species gut commensals on solid media is insufficient for pathogen inhibition, but supernatants from monocultures of these commensal bacteria enriched in acetate confer inhibition against anaerobic growth of the enteric pathogen

Indexed as

EnterobacteriaceaeKlebsiella pneumoniaeAcetatesAnti-Bacterial AgentsBacteriaFatty Acids, VolatileHumansAcetatesAnti-Bacterial AgentsFatty Acids, VolatilebacteriostaticcolonizationEnterobacteriaceaeintestineKlebsiella pneumoniaeshort-chain fatty acids

Identifiers

PMID38305176
PMCPMC10900885
OpenAlexW4391472830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.