Evidence map›Paper›PMID 38305089›Full record

ArticleEpidemiology and infection2024

Seroconversion and seroprevalence of TORCH infections in a pregnant women cohort study, Mombasa, Kenya, 2017-2019.

Elizabeth Hunsperger, Eric Osoro, Peninah Munyua, M Kariuki Njenga, Harriet Mirieri, Gilbert Kikwai, Dennis Odhiambo, Moshe Dayan, Victor Omballa, George O Agogo and 3 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elizabeth HunspergerDivision of Global Health Protection, US Centers for Disease Control and Prevention (CDC), Nairobi, Kenya.ORCID 0000-0002-4450-621X
Eric OsoroWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Peninah MunyuaDivision of Global Health Protection, US Centers for Disease Control and Prevention (CDC), Nairobi, Kenya.
M Kariuki NjengaWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Harriet MirieriWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Gilbert KikwaiKenya Medical Research Institute (KEMRI), Center for Global Health Research, Nairobi, Kenya.
Dennis OdhiamboKenya Medical Research Institute (KEMRI), Center for Global Health Research, Nairobi, Kenya.
Moshe DayanKenya Medical Research Institute (KEMRI), Center for Global Health Research, Nairobi, Kenya.
Victor OmballaKenya Medical Research Institute (KEMRI), Center for Global Health Research, Nairobi, Kenya.
George O AgogoDivision of Global Health Protection, US Centers for Disease Control and Prevention (CDC), Nairobi, Kenya.
Cyrus MugoDepartment of Paediatrics and Child Health/Kenyatta National Hospital, University of Nairobi, Nairobi, Kenya.
Marc-Alain WiddowsonDivision of Global Health Protection, US Centers for Disease Control and Prevention (CDC), Nairobi, Kenya.
Irene InwaniDepartment of Paediatrics and Child Health/Kenyatta National Hospital, University of Nairobi, Nairobi, Kenya.

Funding

ACL HHS U01GH002143CGH CDC HHS 1U01GH002143CGH CDC HHS U01 GH002143
6 · The paper itself

Abstract

Women infected during pregnancy with TORCH (Toxoplasmosis, Other, Rubella, Cytomegalovirus, and Herpes simplex viruses) pathogens have a higher risk of adverse birth outcomes including stillbirth / miscarriage because of mother-to-child transmission. To investigate these risks in pregnant women in Kenya, we analyzed serum specimens from a pregnancy cohort study at three healthcare facilities. A sample of 481 participants was selected for TORCH pathogen antibody testing to determine seroprevalence. A random selection of 285 from the 481 participants was selected to measure seroconversion. These sera were tested using an IgG enzyme-linked immunosorbent assay against 10 TORCH pathogens. We found that the seroprevalence of all but three of the 10 TORCH pathogens at enrollment was >30%, except for

Indexed as

Cytomegalovirus InfectionsPregnancy Complications, InfectiousRubellaSeroconversionAdolescentAdultAntibodies, ViralCohort StudiesFemaleHerpes SimplexHumansKenyaPregnancySeroepidemiologic StudiesToxoplasmosisYoung AdultAntibodies, ViralBordetella pertussisChlamydia trachomatiscytomegalovirusherpes virus type 1 and 2Kenyaparvovirus B19rubellaTORCHToxoplasmosis gondiiTreponema pallidumvaricella zoster virus

Identifiers

PMID38305089
PMCPMC11077605

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.