Evidence map›Paper›PMID 38305063›Full record

ReviewHistology and histopathology2024

Genotype-histotype-phenotype correlations in hyperinsulinemic hypoglycemia.

Annette Rønholt Larsen, Klaus Brusgaard, Henrik Thybo Christesen, Sönke Detlefsen

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Histology and histopathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. [Exercise-induced hyperinsulinism: genetic basis and clinical management].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Review
  2. Article
  3. Necrotizing enterocolitis following a single very low dose of octreotide in a patient with congenital hyperinsulinism: a case successfully managed with 18F-DOPA PET/CT-guided surgery.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Annette Rønholt LarsenHans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark.
Klaus BrusgaardDepartment of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Henrik Thybo Christesen *Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark.
Sönke Detlefsen *Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
University of Southern Denmark · DKOdense University Hospital · DKSteno Diabetes Center · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperinsulinemic hypoglycemia (HH) of pancreatic origin includes congenital hyperinsulinism (CHI), insulinoma, insulinomatosis, and adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia syndrome (NI-PHHS). In this review, we describe the genotype-histotype-phenotype correlations in HH and their therapeutic implications. CHI can occur from birth or later on in life. Histologically, diffuse CHI shows diffuse beta cell hypertrophy with a few giant nuclei per islet of Langerhans, most frequently caused by loss-of-function mutations in

Indexed as

Congenital HyperinsulinismGenetic Association StudiesGenotypeHumansHyperinsulinismHypoglycemiaInsulinomaMutationPancreatic NeoplasmsPhenotype

Identifiers

PMID38305063
OpenAlexW4394753446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.