Evidence map›Paper›PMID 38304811›Full record

ArticleHeliyon2024

Evaluation of the safety and immune stimulatory effects of multi-strain Lab Mix product on laboratory animals.

Duy Ha Nguyen, Thai Son Nguyen, Thi Hong Hanh Le, Quynh Uyen Nguyen, Nhat Le Bui, Dinh Toi Chu, Hoang Van Vinh

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Effects of Lactoferrin andAnimals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Duy Ha NguyenVietnam Military Medical University, Hanoi, Viet Nam.
Thai Son NguyenVietnam Military Medical University, Hanoi, Viet Nam.
Thi Hong Hanh LeVietnam Military Medical University, Hanoi, Viet Nam.
Quynh Uyen NguyenInstitute of Microbiology and Biotechnology, Vietnam National University, Hanoi, Viet Nam.
Nhat Le BuiCenter for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Viet Nam.
Dinh Toi ChuCenter for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Viet Nam.
Hoang Van VinhInstitute of Microbiology and Biotechnology, Vietnam National University, Hanoi, Viet Nam.
Vietnam National University, Hanoi · VNVietnam Military Medical University · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & aims: Probiotics are alive and beneficial bacteria used as food complements with sufficient amounts to improve and balance the intestinal flora in the human gastrointestinal tract and inhibit harmful microorganisms. In this study, we conducted experiments to evaluate he safety and the effect of one of our probiotics on selected biochemical parameters in animal models. Methods: LabMix is a probiotic product containing three bacterial strains, including Results: The LD50 dose in mice of this product could not be determined since no death or disorder was recorded. In rats receiving LabMix with doses of 2.52 × 10 Conclusions: LabMix product is possibly considered safe for human., and this sproduct reduced the release of pro-inflammatory cytokines (IL-6 and TNF-

Indexed as

CytokinesLaboratory animalsMucosal IgA antibodiesProbioticsToxicity

Identifiers

PMID38304811
PMCPMC10831734
OpenAlexW4390859941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.